(Q43743852)

26 November 2017

title

Enzymatic autocatalysis of botulinum A neurotoxin light chain (English)

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26 November 2017

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S A Ahmed

1

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26 November 2017

M P Byrne

2

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26 November 2017

M Jensen

3

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26 November 2017

H B Hines

4

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26 November 2017

E Brueggemann

5

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26 November 2017

L A Smith

6

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26 November 2017

publication date

1 April 2001

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26 November 2017

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26 November 2017

volume

20

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26 November 2017

issue

3

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26 November 2017

page(s)

221-231

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Sequence homology and structural analysis of the clostridial neurotoxins

26 November 2017

cites work

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12 December 2020

Protein-sulfenic acids: diverse roles for an unlikely player in enzyme catalysis and redox regulation

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12 December 2020

Cloning, expression, and one-step purification of the minimal essential domain of the light chain of botulinum neurotoxin type A.

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12 December 2020

Role of zinc binding in type A botulinum neurotoxin light chain's toxic structure

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12 December 2020

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12 December 2020

Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus

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12 December 2020

Evidence for a vesicle-mediated maintenance of store-operated calcium channels in a human embryonic kidney cell line

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12 December 2020

Evolutionarily related insertion pathways of bacterial, mitochondrial, and thylakoid membrane proteins

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12 December 2020

Light chain of botulinum A neurotoxin expressed as an inclusion body from a synthetic gene is catalytically and functionally active

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12 December 2020

Active-site structural comparison of streptococcal NADH peroxidase and NADH oxidase. Reconstitution with artificial flavins

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12 December 2020

Botulinum neurotoxin type A: sequence of amino acids at the N-terminus and around the nicking site

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12 December 2020

The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene

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12 December 2020

Purification and characterization of a protease from Clostridium botulinum type A that nicks single-chain type A botulinum neurotoxin into the di-chain form

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12 December 2020

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

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12 December 2020

C. botulinum neurotoxin types A and E: isolated light chain breaks down into two fragments. Comparison of their amino acid sequences with tetanus neurotoxin

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12 December 2020

Identification of three sites of proteolytic cleavage in the hinge region between the two domains of the beta 2 subunit of tryptophan synthase of Escherichia coli or Salmonella typhimurium

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12 December 2020

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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12 December 2020

Structural analysis of porcine brain nitric oxide synthase reveals a role for tetrahydrobiopterin and L-arginine in the formation of an SDS-resistant dimer.

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12 December 2020

Expression and Purification of the Light Chain of Botulinum Neurotoxin A: A Single Mutation Abolishes Its Cleavage of SNAP-25 and Neurotoxicity after Reconstitution with the Heavy Chain

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12 December 2020

Secondary structural predictions for the clostridial neurotoxins.

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12 December 2020

SNARE motif and neurotoxins

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12 December 2020

Covalent structure of botulinum neurotoxin type A: location of sulfhydryl groups, and disulfide bridges and identification of C-termini of light and heavy chains

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12 December 2020

Chelation of zinc antagonizes the neuromuscular blocking properties of the seven serotypes of botulinum neurotoxin as well as tetanus toxin

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12 December 2020

How to measure and predict the molar absorption coefficient of a protein

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12 December 2020

Proteolysis of synthetic peptides by type A botulinum neurotoxin

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12 December 2020

Structure and function of tetanus and botulinum neurotoxins.

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12 December 2020

Endoproteinase activity of type A botulinum neurotoxin: substrate requirements and activation by serum albumin

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12 December 2020

Protection by the heavy metal chelator N,N,N',N'-tetrakis (2-pyridylmethyl)ethylenediamine (TPEN) against the lethal action of botulinum neurotoxin A and B.

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12 December 2020

Structural features of aminoquinolines necessary for antagonist activity against botulinum neurotoxin

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12 December 2020

Botulinum neurotoxin types A and E require the SNARE motif in SNAP-25 for proteolysis.

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12 December 2020

Role of zinc in the structure and toxic activity of botulinum neurotoxin

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12 December 2020

Type A botulinum neurotoxin proteolytic activity: development of competitive inhibitors and implications for substrate specificity at the S1' binding subsite

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12 December 2020

Crystal structure of botulinum neurotoxin type A and implications for toxicity

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12 December 2020

Identifiers

DOI

10.1023/A:1010952025677

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Dimensions Publication ID

26 November 2017

1002843781

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