(Q43786808)

26 November 2017

The linker domain of the Ha-Ras hypervariable region regulates interactions with exchange factors, Raf-1 and phosphoinositide 3-kinase (English)

1 reference

26 November 2017

4

1 reference

26 November 2017

Jodi Clyde-Smith

3

0 references

Jun Yan

object named as

Jun Yan

series ordinal

2

0 references

author name string

Montserrat Jaumot

series ordinal

1

1 reference

PubMed ID

11689566

26 November 2017

John F Hancock

series ordinal

5

1 reference

PubMed ID

11689566

26 November 2017

language of work or name

English

0 references

publication date

31 October 2001

1 reference

Journal of Biological Chemistry

26 November 2017

1 reference

26 November 2017

277

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26 November 2017

272-278

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26 November 2017

1

1 reference

Increasing complexity of Ras signaling.

26 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

The Ras branch of small GTPases: Ras family members don't fall far from the tree

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

The p21 ras C-terminus is required for transformation and membrane association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

p21ras is modified by a farnesyl isoprenoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

H-ras but not K-ras traffics to the plasma membrane through the exocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Prenylation-dependent association of Ki-Ras with microtubules. Evidence for a role in subcellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

A caveolin dominant negative mutant associates with lipid bodies and induces intracellular cholesterol imbalance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

GTP-dependent segregation of H-ras from lipid rafts is required for biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Transient palmitoylation supports H-Ras membrane binding but only partial biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

N-terminally myristoylated Ras proteins require palmitoylation or a polybasic domain for plasma membrane localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Characterization of RasGRP2, a plasma membrane-targeted, dual specificity Ras/Rap exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

K-ras is an essential gene in the mouse with partial functional overlap with N-ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

The murine N-ras gene is not essential for growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Targeted genomic disruption of H-ras and N-ras, individually or in combination, reveals the dispensability of both loci for mouse growth and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Differential activation of the Rac pathway by Ha-Ras and K-Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Structure and function of the C-terminal hypervariable region of K-Ras4B in plasma membrane targetting and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Activation of mitogen-activated protein kinase by membrane-targeted Raf chimeras is independent of raft localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Cholesterol depletion of caveolae causes hyperactivation of extracellular signal-related kinase (ERK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Agonist-dependent traffic of raft-associated Ras and Raf-1 is required for activation of the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Mutation of Ha-Ras C Terminus Changes Effector Pathway Utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Caveolin and ras function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

The C-terminal polylysine region and methylation of K-Ras are critical for the interaction between K-Ras and microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Mutational and biochemical analysis of plasma membrane targeting mediated by the farnesylated, polybasic carboxy terminus of K-ras4B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Activity of plasma membrane-recruited Raf-1 is regulated by Ras via the Raf zinc finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Endogenous c-N-Ras provides a steady-state anti-apoptotic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Ras isoforms vary in their ability to activate Raf-1 and phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

Molecular dynamics analysis of the structures of ras-guanine nucleotide exchange protein (SOS) bound to wild-type and oncogenic ras-p21. Identification of effector domains of SOS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108423200

21 January 2018

Identifiers

DOI

10.1074/JBC.M108423200

1 reference

26 November 2017

1 reference

PubMed ID

11689566