(Q43990161)

28 November 2017

In vivo phosphorylation of insulin receptor substrate 1 at serine 789 by a novel serine kinase in insulin-resistant rodents (English)

1 reference

28 November 2017

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1 reference

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Li-Ya Qiao

1

1 reference

28 November 2017

Rachel Zhande

2

1 reference

28 November 2017

Thomas L Jetton

3

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28 November 2017

Gaochao Zhou

4

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28 November 2017

Xiao Jian Sun

5

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28 November 2017

language of work or name

English

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publication date

2 May 2002

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Journal of Biological Chemistry

28 November 2017

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28 November 2017

277

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28 November 2017

26530-26539

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28 November 2017

29

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Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

28 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

The insulin signalling system and the IRS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Nck associates with the SH2 domain-docking protein IRS-1 in insulin-stimulated cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

The Fyn tyrosine kinase binds Irs-1 and forms a distinct signaling complex during insulin stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Tumor necrosis factor-alpha- and hyperglycemia-induced insulin resistance. Evidence for different mechanisms and different effects on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

5'-AMP-activated protein kinase phosphorylates IRS-1 on Ser-789 in mouse C2C12 myotubes in response to 5-aminoimidazole-4-carboxamide riboside

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Identification of enhanced serine kinase activity in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Insulin and Obesity in the Zucker Genetically Obese Rat “Fatty”

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Role of IRS-1-GRB-2 complexes in insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Abnormal insulin and glucose metabolism in the JCR:LA-corpulent rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Release of insulin receptor substrate proteins from an intracellular complex coincides with the development of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Signalling through the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

New clues to how proteins link up to run the cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Signaling through scaffold, anchoring, and adaptor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

Molecular mechanism of insulin-induced degradation of insulin receptor substrate 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M201494200

21 January 2018

Identifiers

DOI

10.1074/JBC.M201494200

1 reference

release_xewmzdgqrfc63kov6jnbuefzoe

28 November 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/xewmzdgqrfc63kov6jnbuefzoe

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference