(Q43997248)

28 November 2017

Screening the yeast "disruptome" for mutants affecting resistance to the immunosuppressive drug, mycophenolic acid (English)

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28 November 2017

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Christine Desmoucelles

1

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28 November 2017

Benoit Pinson

2

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28 November 2017

Christelle Saint-Marc

3

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28 November 2017

Bertrand Daignan-Fornier

4

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28 November 2017

language of work or name

English

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publication date

16 May 2002

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Journal of Biological Chemistry

28 November 2017

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28 November 2017

277

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28 November 2017

27036-27044

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28 November 2017

30

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Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid

28 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Proteome analysis and morphological studies reveal multiple effects of the immunosuppressive drug mycophenolic acid specifically resulting from guanylic nucleotide depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Mutations in the second largest subunit of RNA polymerase II cause 6-azauracil sensitivity in yeast and increased transcriptional arrest in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The Rpb9 subunit of RNA polymerase II binds transcription factor TFIIE and interferes with the SAGA and elongator histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The Paf1 complex physically and functionally associates with transcription elongation factors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Regulation of an IMP dehydrogenase gene and its overexpression in drug-sensitive transcription elongation mutants of yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Role of the myb-like protein bas1p in Saccharomyces cerevisiae: a proteome analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Identification of a gene for a polyamine transport protein in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Multidrug-resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames with the major facilitator superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Overexpression of a cloned IMP dehydrogenase gene of Candida albicans confers resistance to the specific inhibitor mycophenolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazole.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Isolation and characterization of mycophenolic acid-resistant mutants of inosine-5'-monophosphate dehydrogenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Species-specific inhibition of inosine 5'-monophosphate dehydrogenase by mycophenolic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Dual requirement for the yeast MMS19 gene in DNA repair and RNA polymerase II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Allosteric binding of nucleoside triphosphates to RNA polymerase regulates transcription elongation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

RNA polymerase II subunit Rpb9 regulates transcription elongation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Saccharomyces cerevisiae transcription elongation mutants are defective in PUR5 induction in response to nucleotide depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Transcriptional regulation of the yeast gmp synthesis pathway by its end products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Genetic interaction between transcription elongation factor TFIIS and RNA polymerase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

DNA topoisomerase-targeting antitumor drugs can be studied in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The Saccharomyces cerevisiae protein Mnn10p/Bed1p is a subunit of a Golgi mannosyltransferase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

The MAPKKK Ste11 regulates vegetative growth through a kinase cascade of shared signaling components

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Characterization of staurosporine-sensitive mutants of Saccharomyces cerevisiae: vacuolar functions affect staurosporine sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Immunosuppressant Target Protein FKBP12 Is Required for P-Glycoprotein Function in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

6-Azauracil inhibition of GTP biosynthesis in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

Mutations sensitizing yeast cells to the start inhibitor nalidixic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111433200

21 January 2018

Identifiers

DOI

10.1074/JBC.M111433200

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28 November 2017

1 reference