(Q44038918)

29 November 2017

The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model (English)

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29 November 2017

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M K Nyati

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29 November 2017

Z Symon

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29 November 2017

E Kievit

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29 November 2017

K J Dornfeld

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29 November 2017

S D Rynkiewicz

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29 November 2017

B D Ross

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29 November 2017

A Rehemtulla

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29 November 2017

T S Lawrence

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29 November 2017

1 July 2002

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29 November 2017

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844-849

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29 November 2017

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3301706

29 November 2017

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cites work

Regional delivery of an adenovirus vector containing the Escherichia coli cytosine deaminase gene to provide local activation of 5-fluorocytosine to suppress the growth of colon carcinoma metastatic to liver.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Enzyme/prodrug therapy for head and neck cancer using a catalytically superior cytosine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Gene therapy of metastatic colon carcinoma: regression of multiple hepatic metastases by adenoviral expression of bacterial cytosine deaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Transfer of the bacterial gene for cytosine deaminase to mammalian cells confers lethal sensitivity to 5-fluorocytosine: a negative selection system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Orthotopic implantation of human colon carcinomas into nude mice provides a valuable model for the biology and therapy of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

In vivo adenovirus-mediated gene transfer of the Escherichia coli cytosine deaminase gene to human colon carcinoma-derived tumors induces chemosensitivity to 5-fluorocytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Evidence for conversion of 5-fluorocytosine to 5-fluorouracil in humans: possible factor in 5-fluorocytosine clinical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Conversion of 5-fluorocytosine to 5-fluorouracil by human intestinal microflora

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Use of reporter genes for optical measurements of neoplastic disease in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

Diffusion MRI detects early events in the response of a glioma model to the yeast cytosine deaminase gene therapy strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301706

21 January 2018

Identifiers

DOI

10.1038/SJ.GT.3301706

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29 November 2017

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