(Q44050802)

29 November 2017

title

Pirfenidone suppresses tumor necrosis factor-alpha, enhances interleukin-10 and protects mice from endotoxic shock (English)

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29 November 2017

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Hisashi Oku

1

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29 November 2017

Hitoshi Nakazato

2

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29 November 2017

Tatsuya Horikawa

3

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29 November 2017

Yuji Tsuruta

4

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29 November 2017

Ryuji Suzuki

5

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29 November 2017

language of work or name

English

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publication date

1 June 2002

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European Journal of Pharmacology

29 November 2017

published in

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29 November 2017

volume

446

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29 November 2017

issue

1-3

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29 November 2017

page(s)

167-176

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Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivo

29 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901757-0

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7 January 2021

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The biology of cachectin/TNF--a primary mediator of the host response

7 January 2021

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Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

7 January 2021

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Inhibition of tumor necrosis factor and subsequent endotoxin shock by pirfenidone

7 January 2021

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Interferon gamma receptor deficient mice are resistant to endotoxic shock

7 January 2021

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Endotoxemia in human septic shock

7 January 2021

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Galactosamine-induced sensitization to the lethal effects of endotoxin

7 January 2021

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Mechanisms of the hemodynamic effects of endotoxin

7 January 2021

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Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of gamma interferon

7 January 2021

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Interleukin 10 protects mice from lethal endotoxemia

7 January 2021

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Pirfenidone diminishes cyclophosphamide-induced lung fibrosis in mice

7 January 2021

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Secretion of macrophage-derived growth factor during acute lung injury induced by bleomycin

7 January 2021

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Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice

7 January 2021

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7 January 2021

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7 January 2021

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IL-12-deficient mice are defective but not devoid of type 1 cytokine responses.

7 January 2021

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Interleukin 10 treatment reduces fibrosis in patients with chronic hepatitis C: a pilot trial of interferon nonresponders

7 January 2021

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7 January 2021

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Interleukin 12, interferon gamma, and tumor necrosis factor alpha are the key cytokines of the generalized Shwartzman reaction

7 January 2021

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

7 January 2021

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7 January 2021

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Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label Phase II study

7 January 2021

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Early cellular events in pulmonary fibrosis

7 January 2021

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Pirfenidone improves renal function and fibrosis in the post-obstructed kidney

7 January 2021

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Molecular pathogenesis of interstitial pneumonitis with TNF-alpha transgenic mice

7 January 2021

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Pharmacokinetics of an antifibrotic agent, pirfenidone, in haemodialysis patients.

7 January 2021

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Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia

7 January 2021

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7 January 2021

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7 January 2021

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TNF-alpha, PDGF, and TGF-beta(1) expression by primary mouse bronchiolar-alveolar epithelial and mesenchymal cells: tnf-alpha induces TGF-beta(1)

7 January 2021

1 reference

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Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

7 January 2021

1 reference

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Preventive effect of pirfenidone against experimental sclerosing peritonitis in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2802%2901757-0

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0014-2999(02)01757-0

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29 November 2017

1 reference