(Q44077732)

29 November 2017

title

In vitro cleavage of the MLL gene by topoisomerase II inhibitor (etoposide) in normal cord and peripheral blood mononuclear cells (English)

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29 November 2017

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Eiichi Ishii

1

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29 November 2017

Mariko Eguchi

2

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29 November 2017

Minenori Eguchi-Ishimae

3

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29 November 2017

Nobuyuki Yoshida

4

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29 November 2017

Megumi Oda

5

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29 November 2017

Masafumi Zaitsu

6

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29 November 2017

Ichiro Fujita

7

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29 November 2017

Sumio Miyazaki

8

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29 November 2017

Yuhei Hamasaki

9

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29 November 2017

Shuki Mizutani

10

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29 November 2017

publication date

1 July 2002

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International Journal of Hematology

29 November 2017

published in

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29 November 2017

volume

76

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29 November 2017

issue

1

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29 November 2017

page(s)

74-79

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Structure of nonhairpin coding-end DNA breaks in cells undergoing V(D)J recombination

29 November 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FBF02982722

DNA cleavage within the MLL breakpoint cluster region is a specific event which occurs as part of higher-order chromatin fragmentation during the initial stages of apoptosis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FBF02982722

Infant leukaemia biology, aetiology and treatment

21 January 2018

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12 December 2020

Secondary acute myeloid leukemia in children with acute lymphoblastic leukemia treated with etoposide

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12 December 2020

Maternal exposure to potential inhibitors of DNA topoisomerase II and infant leukemia (United States): a report from the Children's Cancer Group.

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12 December 2020

Infant acute leukemias show the same biased distribution of ALL1 gene breaks as topoisomerase II related secondary acute leukemias.

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12 December 2020

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

1 reference

12 December 2020

Intrauterine monoclonal origin of neonatal concordant acute lymphoblastic leukemia in monozygotic twins

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12 December 2020

Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends

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12 December 2020

A consensus sequence for cleavage by vertebrate DNA topoisomerase II.

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12 December 2020

Biology and treatment of acute lymphoblastic leukemia

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12 December 2020

Infant leukemia in Japan: clinical and biological analysis of 48 cases

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12 December 2020

Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion.

1 reference

12 December 2020

Site-specific DNA cleavage within the MLL breakpoint cluster region induced by topoisomerase II inhibitors.

1 reference

12 December 2020

High frequency of fusion transcripts of exon 11 and exon 4/5 in AF-4 gene is observed in cord blood, as well as leukemic cells from infant leukemia patients with t(4;11)(q21;q23)

1 reference

12 December 2020

Double-strand signal sequence breaks in V(D)J recombination are blunt, 5'-phosphorylated, RAG-dependent, and cell cycle regulated

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12 December 2020

Molecular analysis of the chromosomal breakpoint and fusion transcripts in the acute lymphoblastic SEM cell line with chromosomal translocation t(4;11).

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12 December 2020

The partial tandem duplication of ALL1 (MLL) is consistently generated by Alu-mediated homologous recombination in acute myeloid leukemia

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12 December 2020

Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites

1 reference

12 December 2020

Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia.

1 reference

12 December 2020

Etoposide metabolites enhance DNA topoisomerase II cleavage near leukemia-associated MLL translocation breakpoints

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12 December 2020

An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region

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12 December 2020

Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II

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12 December 2020

Secondary acute myeloid leukemia in children previously treated with alkylating agents, intercalating topoisomerase II inhibitors, and irradiation

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12 December 2020

Breakage and fusion of the TEL (ETV6) gene in immature B lymphocytes induced by apoptogenic signals

1 reference

12 December 2020

Dietary flavonoids and the MLL gene: A pathway to infant leukemia?

1 reference

12 December 2020

Cloning and sequence analysis of four t(9;11) therapy-related leukemia breakpoints

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12 December 2020

In utero rearrangements in the trithorax-related oncogene in infant leukaemias.

1 reference

12 December 2020

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

1 reference

12 December 2020

Molecular analysis of 13 cases of MLL/11q23 secondary acute leukemia and identification of topoisomerase II consensus-binding sequences near the chromosomal breakpoint of a secondary leukemia with the t(4;11).

1 reference

12 December 2020

Secondary leukemias induced by topoisomerase-targeted drugs

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12 December 2020

Identifiers

DOI

10.1007/BF02982722

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29 November 2017

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