(Q44138744)

English

Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1.

scientific article published on 13 September 2002

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scholarly article

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Europe PubMed Central

30 November 2017

Structural and functional consequences of mutating cysteine residues in the amino terminus of human multidrug resistance-associated protein 1. (English)

1 reference

Europe PubMed Central

30 November 2017

multiple drug resistance

1 reference

based on heuristic

inferred from title

author name string

Youyun Yang

1

1 reference

Europe PubMed Central

30 November 2017

Qun Chen

2

1 reference

Europe PubMed Central

30 November 2017

Jian-Ting Zhang

3

1 reference

Europe PubMed Central

30 November 2017

language of work or name

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publication date

13 September 2002

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Europe PubMed Central

30 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

30 November 2017

277

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Europe PubMed Central

30 November 2017

44268-44277

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Europe PubMed Central

30 November 2017

46

1 reference

Europe PubMed Central

30 November 2017

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

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21 January 2018

Plant ABC transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

The human ATP-binding cassette (ABC) transporter superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance.

1 reference

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21 January 2018

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins

1 reference

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21 January 2018

The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

1 reference

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21 January 2018

Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Structural, mechanistic and clinical aspects of MRP1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Membrane topology and glycosylation of the human multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Cytoplasmic retraction of the amino terminus of human multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Multidrug resistance protein. Identification of regions required for active transport of leukotriene C4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Topological folding and proteolysis profile of P-glycoprotein in membranes of multidrug-resistant cells: implications for the drug-transport mechanism.

1 reference

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21 January 2018

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

1 reference

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21 January 2018

Identification of an amino acid residue in multidrug resistance protein 1 critical for conferring resistance to anthracyclines

1 reference

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21 January 2018

Identification of a nonconserved amino acid residue in multidrug resistance protein 1 important for determining substrate specificity: evidence for functional interaction between transmembrane helices 14 and 17.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Conformational changes of P-glycoprotein by nucleotide binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

The multidrug resistance protein 1: a functionally important activation marker for murine Th1 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Nucleotide-induced conformational changes in the human multidrug resistance protein MRP1 are related to the capacity of chemotherapeutic drugs to accumulate or not in resistant cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Characterization of binding of leukotriene C4 by human multidrug resistance protein 1: evidence of differential interactions with NH2- and COOH-proximal halves of the protein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Functional evidence that transmembrane 12 and the loop between transmembrane 11 and 12 form part of the drug-binding domain in P-glycoprotein encoded by MDR1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Drug-stimulated ATPase activity of human P-glycoprotein is blocked by disulfide cross-linking between the nucleotide-binding sites.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Identification of Residues in the Drug-binding Domain of Human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Identification of Residues within the Drug-binding Domain of the Human Multidrug Resistance P-glycoprotein by Cysteine-scanning Mutagenesis and Reaction with Dibromobimane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Localization of a Substrate Specificity Domain in the Multidrug Resistance Protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Major photoaffinity drug binding sites in multidrug resistance protein 1 (MRP1) are within transmembrane domains 10-11 and 16-17

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M207003200

21 January 2018

The multidrug resistance protein is photoaffinity labeled by a quinoline-based drug at multiple sites

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M207003200

1 reference

Europe PubMed Central

30 November 2017

1 reference

Europe PubMed Central

30 November 2017

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