(Q44319734)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12592346%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells (English)

1 reference

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31 October 2019

5

1 reference

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31 October 2019

author name string

Bolick SC

1

1 reference

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31 October 2019

Landowski TH

2

1 reference

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31 October 2019

Boulware D

3

1 reference

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31 October 2019

Oshiro MM

4

1 reference

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31 October 2019

Hamilton AD

6

1 reference

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31 October 2019

Sebti SM

7

1 reference

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31 October 2019

Dalton WS

8

1 reference

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31 October 2019

publication date

1 February 2003

1 reference

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31 October 2019

1 reference

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31 October 2019

volume

17

1 reference

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31 October 2019

page(s)

451-457

1 reference

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31 October 2019

issue

2

1 reference

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https://scigraph.springernature.com/pub.10.1038/sj.leu.2402832

31 October 2019

exact match

0 references

cites work

Ras oncogene mutation in multiple myeloma

1 reference

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Verapamil suppresses the emergence of P-glycoprotein-mediated multi-drug resistance

21 January 2018

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All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

1 reference

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The p21 ras C-terminus is required for transformation and membrane association

21 January 2018

1 reference

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Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832

Farnesyltransferase and geranylgeranyltransferase I inhibitors in cancer therapy: important mechanistic and bench to bedside issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832

Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832

The farnesyl transferase inhibitor SCH 66336 induces a G(2) --> M or G(1) pause in sensitive human tumor cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832

K- and N-Ras are geranylgeranylated in cells treated with farnesyl protein transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832

Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832

Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402832