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Proliferation of cancer cells despite CDK2 inhibition.
scientific article published in March 2003
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
title
Proliferation of cancer cells despite CDK2 inhibition
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author
Osamu Tetsu
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
author name string
Frank McCormick
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
publication date
1 March 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
published in
Cancer Cell
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
volume
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
page(s)
233-245
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
cites work
Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.
1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
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retrieved
7 January 2021
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inferred from DOI database lookup
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1 reference
stated in
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retrieved
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
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based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of CDK4 sequences involved in cyclin D1 and p16 binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Specificity and mechanism of action of some commonly used protein kinase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Retinoic acid and the cyclin dependent kinase inhibitors synergistically alter proliferation and morphology of U343 astrocytoma cells
1 reference
stated in
Crossref
reference URL
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retrieved
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based on heuristic
inferred from DOI database lookup
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
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retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of retinoblastoma protein functions by ectopic expression of human cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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inferred from DOI database lookup
S and G2 phase roles for Cdk2 revealed by inducible expression of a dominant-negative mutant in human cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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based on heuristic
inferred from DOI database lookup
Requirement of cyclin E-Cdk2 inhibition in p16(INK4a)-mediated growth suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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based on heuristic
inferred from DOI database lookup
Regulation of cyclin D-dependent kinase 4 (cdk4) by cdk4-activating kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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based on heuristic
inferred from DOI database lookup
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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based on heuristic
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Cyclin D1 is dispensable for G1 control in retinoblastoma gene-deficient cells independently of cdk4 activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
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stated in
Crossref
reference URL
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
retrieved
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Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
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stated in
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stated in
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retrieved
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Crossref
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1 reference
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1 reference
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1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900053-9
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7 January 2021
based on heuristic
inferred from DOI database lookup
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1 reference
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reference URL
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p27 Kip1 inhibits HER2/neu-mediated cell growth and tumorigenesis
1 reference
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Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases
1 reference
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1 reference
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7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1535-6108(03)00053-9
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
PubMed ID
12676582
1 reference
stated in
Europe PubMed Central
PubMed ID
12676582
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12676582%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 November 2019
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