(Q44478685)

English

Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.

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scholarly article

1 reference

Europe PubMed Central

3 December 2017

Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt. (English)

1 reference

Europe PubMed Central

3 December 2017

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reactive oxygen species

1 reference

based on heuristic

inferred from title

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Ju-Hyung Woo

1

1 reference

Europe PubMed Central

3 December 2017

Young-Ho Kim

2

1 reference

Europe PubMed Central

3 December 2017

Yun-Jung Choi

3

1 reference

Europe PubMed Central

3 December 2017

Dae-Gon Kim

4

1 reference

Europe PubMed Central

3 December 2017

Kyung-Seop Lee

5

1 reference

Europe PubMed Central

3 December 2017

Jae Hoon Bae

6

1 reference

Europe PubMed Central

3 December 2017

Do Sik Min

7

1 reference

Europe PubMed Central

3 December 2017

Jong-Soo Chang

8

1 reference

Europe PubMed Central

3 December 2017

Yong-Jin Jeong

9

1 reference

Europe PubMed Central

3 December 2017

Young Han Lee

10

1 reference

Europe PubMed Central

3 December 2017

Jong-Wook Park

11

1 reference

Europe PubMed Central

3 December 2017

Taeg Kyu Kwon

12

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Europe PubMed Central

3 December 2017

language of work or name

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publication date

9 May 2003

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Europe PubMed Central

3 December 2017

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Europe PubMed Central

3 December 2017

24

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Europe PubMed Central

3 December 2017

1199-1208

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Europe PubMed Central

3 December 2017

7

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Europe PubMed Central

3 December 2017

Pharmacology of Curcuma longa

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Inhibitory effects of curcumin on protein kinase C activity induced by 12-O-tetradecanoyl-phorbol-13-acetate in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Suppression of c-Jun/AP-1 activation by an inhibitor of tumor promotion in mouse fibroblast cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Inhibition of invasion and induction of apoptosis by curcumin in H-ras-transformed MCF10A human breast epithelial cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Free radicals as mediators of tissue injury and disease

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

[38] Detection of reactive nitrogen species using 2,7-dichlorodihydrfluorescein and dihydrorhodamine 123

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Apoptosis in the pathogenesis and treatment of disease

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Reactive oxygen species and programmed cell death

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Akt regulates cell survival and apoptosis at a postmitochondrial level

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

IAP family proteins--suppressors of apoptosis

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Role of reactive oxygen species (ROS) in apoptosis induction

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Curcumin induces caspase-3-independent apoptosis in human multidrug-resistant cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

A novel apoptosis-like pathway, independent of mitochondria and caspases, induced by curcumin in human lymphoblastoid T (Jurkat) cells.

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Effect of glutathione depletion on caspase-3 independent apoptosis pathway induced by curcumin in Jurkat cells

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGG082

21 January 2018

Identifiers

10.1093/CARCIN/BGG082

1 reference

Europe PubMed Central

3 December 2017

1 reference

Europe PubMed Central

3 December 2017

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