(Q44530875)

3 December 2017

title

Ligand-mediated activation of the cAMP-responsive guanine nucleotide exchange factor Epac (English)

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3 December 2017

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4

Alfred Wittinghofer

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3 December 2017

Stein O Døskeland

3

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author name string

Holger Rehmann

series ordinal

1

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3 December 2017

Frank Schwede

series ordinal

2

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3 December 2017

Johannes L Bos

series ordinal

5

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3 December 2017

language of work or name

English

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publication date

29 July 2003

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Journal of Biological Chemistry

3 December 2017

published in

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3 December 2017

volume

278

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3 December 2017

issue

40

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3 December 2017

page(s)

38548-38556

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Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

3 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

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The structural basis of the activation of Ras by Sos

21 January 2018

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Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Structure and regulation of the cAMP-binding domains of Epac2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Regulatory subunit of protein kinase A: structure of deletion mutant with cAMP binding domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Communication between the regulatory and the catalytic region of the cAMP-responsive guanine nucleotide exchange factor Epac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Dynamic interaction of cAMP with the Rap guanine-nucleotide exchange factor Epac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Fast and slow cyclic nucleotide-dissociation sites in cAMP-dependent protein kinase are transposed in type Ibeta cGMP-dependent protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Epac-selective cAMP analog 8-pCPT-2'-O-Me-cAMP as a stimulus for Ca2+-induced Ca2+ release and exocytosis in pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Predicted structures of the cGMP binding domains of the cGMP-dependent protein kinase: a key alanine/threonine difference in evolutionary divergence of cAMP and cGMP binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Dissecting cAMP binding domain A in the RIalpha subunit of cAMP-dependent protein kinase. Distinct subsites for recognition of cAMP and the catalytic subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3',5'-monophosphorothioates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

cAMP analog mapping of Epac1 and cAMP kinase. Discriminating analogs demonstrate that Epac and cAMP kinase act synergistically to promote PC-12 cell neurite extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M306292200

21 January 2018

Identifiers

DOI

10.1074/JBC.M306292200

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3 December 2017

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