(Q44643987)

5 December 2017

An aberrant protein synthesis activity is linked with antibiotic overproduction in rpsL mutants of Streptomyces coelicolor A3(2) (English)

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Streptomyces albidoflavus

28 March 2024

main subject

Streptomyces coelicolor

1 reference

inferred from

reverse claim

1 reference

1 reference

bacterial gene expression regulation

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14600242

28 March 2024

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

28 March 2024

author name string

Yoshiko Okamoto-Hosoya

1

1 reference

5 December 2017

Takeshi Hosaka

2

1 reference

5 December 2017

Kozo Ochi

3

1 reference

5 December 2017

language of work or name

English

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14600242

28 March 2024

publication date

1 November 2003

1 reference

full work available at URL

5 December 2017

https://www.microbiologyresearch.org/content/journal/micro/10.1099/mic.0.26490-0?crawler=true

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

28 March 2024

1 reference

5 December 2017

149

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5 December 2017

3299-3309

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5 December 2017

Pt 11

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Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

5 December 2017

1

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Kinetic properties of Escherichia coli ribosomes with altered forms of S12

28 March 2024

2

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

28 March 2024

3

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

The ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2) plays a conditional role in antibiotic production and morphological differentiation

28 March 2024

5

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Cloning, characterization and disruption of a (p)ppGpp synthetase gene (relA) of Streptomyces coelicolor A3(2).

28 March 2024

6

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces

28 March 2024

9

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Use of Brij lysis as a general method to prepare polyribosomes from Escherichia coli

28 March 2024

10

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Streptomycin-resistant and streptomycin-dependent mutants of the extreme thermophile Thermus thermophilus

28 March 2024

11

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

A novel method for improving Streptomyces coelicolor A3(2) for production of actinorhodin by introduction of rpsL (encoding ribosomal protein S12) mutations conferring resistance to streptomycin

28 March 2024

12

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Acquisition of certain streptomycin-resistant (str) mutations enhances antibiotic production in bacteria

28 March 2024

14

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Novel approach for improving the productivity of antibiotic-producing strains by inducing combined resistant mutations

28 March 2024

15

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans

28 March 2024

16

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Construction of an in vivo nonsense readthrough assay system and functional analysis of ribosomal proteins S12, S4, and S5 in Bacillus subtilis

28 March 2024

17

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Relationship between changes in the translational apparatus and actinomycin production in Streptomyces antibioticus

28 March 2024

18

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Dissociation rates of peptidyl-tRNA from the P-site of E.coli ribosomes.

28 March 2024

19

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Genetic and physiological characterization of rpoB mutations that activate antibiotic production in Streptomyces lividans

28 March 2024

22

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

A relA/spoT homologous gene from Streptomyces coelicolor A3(2) controls antibiotic biosynthetic genes

28 March 2024

24

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

The suppression of defective translation by ppGpp and its role in the stringent response

28 March 2024

26

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Occurrence of the stringent response in Streptomyces sp. and its significance for the initiation of morphological and physiological differentiation

28 March 2024

27

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Metabolic initiation of differentiation and secondary metabolism by Streptomyces griseus: significance of the stringent response (ppGpp) and GTP content in relation to A factor

28 March 2024

28

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

A relaxed (rel) mutant of Streptomyces coelicolor A3(2) with a missing ribosomal protein lacks the ability to accumulate ppGpp, A-factor and prodigiosin.

28 March 2024

29

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Starvation in vivo for aminoacyl-tRNA increases the spatial separation between the two ribosomal subunits.

28 March 2024

31

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Resistance to paromomycin is conferred by rpsL mutations, accompanied by an enhanced antibiotic production in Streptomyces coelicolor A3(2)

28 March 2024

32

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Development of antibiotic-overproducing strains by site-directed mutagenesis of the rpsL gene in Streptomyces lividans

28 March 2024

33

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Structure of functionally activated small ribosomal subunit at 3.3 angstroms resolution

28 March 2024

35

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).

28 March 2024

37

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Charging levels of four tRNA species in Escherichia coli Rel(+) and Rel(-) strains during amino acid starvation: a simple model for the effect of ppGpp on translational accuracy.

28 March 2024

38

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

High concentrations of ppGpp decrease the RNA chain growth rate. Implications for protein synthesis and translational fidelity during amino acid starvation in Escherichia coli.

28 March 2024

39

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Arrangement of tRNAs in pre- and posttranslocational ribosomes revealed by electron cryomicroscopy.

28 March 2024

40

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

The stringent response in Streptomyces coelicolor A3(2)

28 March 2024

41

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Transcriptional regulation of the redD transcriptional activator gene accounts for growth-phase-dependent production of the antibiotic undecylprodigiosin in Streptomyces coelicolor A3(2)

28 March 2024

42

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Mutant sequences in the rpsL gene of Escherichia coli B/r: mechanistic implications for spontaneous and ultraviolet light mutagenesis.

28 March 2024

43

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Modelling in Escherichia coli of mutations in mitoribosomal protein S12: novel mutant phenotypes of rpsL.

28 March 2024

44

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Developmental control of stress stimulons in Streptomyces coelicolor revealed by statistical analyses of global gene expression patterns

28 March 2024

45

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Structure of the 30S ribosomal subunit

28 March 2024

46

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

A rifampicin resistance mutation in the rpoB gene confers ppGpp-independent antibiotic production in Streptomyces coelicolor A3(2).

28 March 2024

47

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Crystal structure of the ribosome at 5.5 A resolution

28 March 2024

48

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

Visualization of a Large Conformation Change of Ribosomes inEscherichia coliCells Starved for Tryptophan or Treated with Kirromycin

28 March 2024

49

1 reference

https://api.crossref.org/works/10.1099/MIC.0.26490-0

28 March 2024

Identifiers

1 reference

5 December 2017

1 reference