(Q44723213)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715958%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

title

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia (English)

1 reference

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17 November 2019

1 reference

Louise McCullough

1

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17 November 2019

Liejun Wu

2

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17 November 2019

Norman Haughey

3

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17 November 2019

Xibin Liang

4

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17 November 2019

Tracey Hand

5

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17 November 2019

Qian Wang

6

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17 November 2019

Richard M Breyer

7

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17 November 2019

Katrin Andreasson

8

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17 November 2019

language of work or name

English

0 references

publication date

1 January 2004

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17 November 2019

published in

Journal of Neuroscience

1 reference

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17 November 2019

volume

24

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17 November 2019

issue

1

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17 November 2019

page(s)

257-268

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Arachidonic acid is preferentially metabolized by cyclooxygenase-2 to prostacyclin and prostaglandin E2

17 November 2019

cites work

1 reference

12 December 2020

A novel subtype of prostacyclin receptor in the central nervous system

1 reference

12 December 2020

Function of microglia in organotypic slice cultures

1 reference

12 December 2020

17beta-estradiol reduces stroke injury in estrogen-deficient female animals

1 reference

12 December 2020

Distribution, regulation and colocalization of the genes encoding the EP2- and EP4-PGE2 receptors in the rat brain and neuronal responses to systemic inflammation

1 reference

12 December 2020

Prostaglandin E(2) stimulates glutamate receptor-dependent astrocyte neuromodulation in cultured hippocampal cells

1 reference

12 December 2020

Overexpression of cyclooxygenase-2 induces cell cycle arrest. Evidence for a prostaglandin-independent mechanism

1 reference

12 December 2020

Estrogen receptor antagonist ICI182,780 exacerbates ischemic injury in female mouse

1 reference

12 December 2020

Is CREB a key to neuronal survival?

1 reference

12 December 2020

Microglial response to brain injury: a brief synopsis

1 reference

12 December 2020

Stroke in estrogen receptor-alpha-deficient mice

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12 December 2020

Cyclooxygenase-2 contributes to N-methyl-D-aspartate-mediated neuronal cell death in primary cortical cell culture

1 reference

12 December 2020

EP(2) receptor mediates bronchodilation by PGE(2) in mice.

1 reference

12 December 2020

U-46619, a selective thromboxane A2 mimetic, inhibits the release of endogenous noradrenaline from the rat hippocampus in vitro

1 reference

12 December 2020

Distribution of the EP3 prostaglandin E(2) receptor subtype in the rat brain: relationship to sites of interleukin-1-induced cellular responsiveness

1 reference

12 December 2020

Organotypic hippocampal cultures. A model of brain tissue damage in Streptococcus pneumoniae meningitis

1 reference

12 December 2020

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

1 reference

12 December 2020

Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke

1 reference

12 December 2020

Prostanoid receptors: subtypes and signaling

1 reference

12 December 2020

Coexpression of microsomal-type prostaglandin E synthase with cyclooxygenase-2 in brain endothelial cells of rats during endotoxin-induced fever.

1 reference

12 December 2020

Prostaglandin release by spinal cord injury mediates production of hydroxyl radical, malondialdehyde and cell death: a site of the neuroprotective action of methylprednisolone.

1 reference

12 December 2020

Proteolysis of glutamate receptor-interacting protein by calpain in rat brain: implications for synaptic plasticity

1 reference

12 December 2020

Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep

1 reference

12 December 2020

Age-dependent cognitive deficits and neuronal apoptosis in cyclooxygenase-2 transgenic mice.

1 reference

12 December 2020

Chronic exposure of kainate and NBQX changes AMPA toxicity in hippocampal slice cultures

1 reference

12 December 2020

Prostaglandin E(2) induces caspase-dependent apoptosis in rat cortical cells

1 reference

12 December 2020

Development of a highly selective EP2-receptor agonist. Part 2: identification of 16-hydroxy-17,17-trimethylene 9beta-chloro PGF derivatives

1 reference

12 December 2020

Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology

1 reference

12 December 2020

Proinflammatory effects of M-CSF and A beta in hippocampal organotypic cultures

1 reference

12 December 2020

Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity

1 reference

12 December 2020

Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity

1 reference

12 December 2020

Cyclooxygenase-2-deficient mice are resistant to 1-methyl-4-phenyl1, 2, 3, 6-tetrahydropyridine-induced damage of dopaminergic neurons in the substantia nigra.

1 reference

12 December 2020

A novel mechanism of dendritic spine plasticity involving estradiol induction of prostaglandin-E2.

1 reference

12 December 2020

Macrophage colony stimulating factor prevents NMDA-induced neuronal death in hippocampal organotypic cultures

1 reference

12 December 2020

Neuronal oxidative damage from activated innate immunity is EP2 receptor-dependent

1 reference

12 December 2020

Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS.

1 reference

12 December 2020

Neuroprotection of cultured cortical neurons mediated by the cyclooxygenase-2 inhibitor APHS can be reversed by a prostanoid

1 reference

12 December 2020

A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

1 reference

12 December 2020

Targeted gene disruption of the prostaglandin E2 EP2 receptor.

1 reference

12 December 2020

Neuronal overexpression of COX-2 results in dominant production of PGE2 and altered fever response

1 reference

12 December 2020

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

1 reference

12 December 2020

Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction.

1 reference

12 December 2020

The presence of thromboxane A2 receptors in cultured astrocytes from rabbit brain

1 reference

12 December 2020

The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801.

1 reference

12 December 2020

Aromatase Cytochrome P450 and Extragonadal Estrogen Play a Role in Ischemic Neuroprotection

1 reference

12 December 2020

Immunohistochemical localization of prostaglandin F2 alpha in reperfused gerbil brain

1 reference

12 December 2020

A simple method for organotypic cultures of nervous tissue

1 reference

12 December 2020

Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures

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12 December 2020

Prostaglandin and thromboxane biosynthesis

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12 December 2020

Prostaglandin H synthase and xenobiotic oxidation

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12 December 2020

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12 December 2020

Reversible middle cerebral artery occlusion without craniectomy in rats

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12 December 2020

cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor

1 reference

12 December 2020

NMDA receptors activate the arachidonic acid cascade system in striatal neurons

1 reference

12 December 2020

Specific bindings of prostaglandin D2, E2 and F2 alpha in postmortem human brain

1 reference

12 December 2020

Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979.

1 reference

12 December 2020

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases

1 reference

12 December 2020

Measurement of local cerebral blood flow with [14C]iodoantipyrine in the mouse

1 reference

12 December 2020

Immunohistochemical demonstration of increase in prostaglandin F2-alpha after recirculation in global ischemic rat brains

1 reference

12 December 2020

The formation and regional distribution of prostaglandins D2 and F2 alpha in the brain of spontaneously convulsing gerbils

1 reference

12 December 2020

Glutamate and non-glutamate receptor mediated toxicity caused by oxygen and glucose deprivation in organotypic hippocampal cultures

1 reference

12 December 2020

Prostaglandin E2 stimulates glutamate release from synaptosomes of rat spinal cord

1 reference

12 December 2020

Prostacyclin receptor in the brain and central terminals of the primary sensory neurons: an autoradiographic study using a stable prostacyclin analogue [3H]iloprost

1 reference

12 December 2020

Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/Kainate receptors in organotypic hippocampal cultures.

1 reference

12 December 2020

Molecular Characterization of the Mouse Prostanoid EP1 Receptor Gene

1 reference

12 December 2020

Enzymatic oxidation of dopamine: the role of prostaglandin H synthase

1 reference

12 December 2020

Distribution of the messenger RNA for the prostaglandin E receptor subtype EP3 in the mouse nervous system

1 reference

12 December 2020

Prostaglandin E2 protects cultured cortical neurons against N-methyl-D-aspartate receptor-mediated glutamate cytotoxicity

1 reference

12 December 2020

Protection by prostaglandins from glutamate toxicity in cortical neurons

1 reference

12 December 2020

Phloretin as an antagonist of prostaglandin F2 alpha receptor in cultured rat astrocytes

1 reference

12 December 2020

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

12 December 2020

Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoids

1 reference

12 December 2020

Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats

1 reference

12 December 2020

Prostaglandin F2 alpha synthesis in the hippocampal mossy fiber synaptosomal preparation: I. Dependence in arachidonic acid, phospholipase A2, calcium availability and membrane depolarization

1 reference

12 December 2020

Cyclooxygenase-2 induction in cerebral cortex: an intracellular response to synaptic excitation

1 reference

12 December 2020

A molecular analysis of PGE receptor (EP) expression on normal and transformed B lymphocytes: coexpression of EP1, EP2, EP3beta and EP4.

1 reference

12 December 2020

AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked.

1 reference

12 December 2020

Thromboxane A2 agonist modulation of excitatory synaptic transmission in the rat hippocampal slice

1 reference

12 December 2020

Novel intracellular signaling function of prostaglandin H synthase-1 in NF-kappa B activation

1 reference

12 December 2020

TXA2 agonists inhibit high-voltage-activated calcium channels in rat hippocampal CA1 neurons

1 reference

12 December 2020

Resting microglial cells in vitro: analysis of morphology and adhesion molecule expression in organotypic hippocampal slice cultures

1 reference

12 December 2020

Prostaglandin F2alpha is required for NMDA receptor-mediated induction of c-fos mRNA in dentate gyrus neurons.

1 reference

12 December 2020

Cyclo-oxygenase-2 gene expression in neurons contributes to ischemic brain damage

1 reference

12 December 2020

Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins.

1 reference

12 December 2020

Spreading depression and focal brain ischemia induce cyclooxygenase-2 in cortical neurons through N-methyl-D-aspartic acid-receptors and phospholipase A2

1 reference

12 December 2020

Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells

1 reference

12 December 2020

Expression of messenger RNA for the prostaglandin D receptor in the leptomeninges of the mouse brain

1 reference

12 December 2020

The identification and characterization of oligodendrocyte thromboxane A2 receptors

1 reference

12 December 2020

Prostaglandins stimulate calcium-dependent glutamate release in astrocytes.

1 reference

12 December 2020

Gender-linked brain injury in experimental stroke

1 reference

12 December 2020

Heterogeneity in the molecular composition of excitatory postsynaptic sites during development of hippocampal neurons in culture.

1 reference

12 December 2020

Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production.

1 reference

12 December 2020

Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes

1 reference

12 December 2020

Cell culture models for reactive gliosis: new perspectives

1 reference

12 December 2020

Prostaglandins act as neurotoxin for differentiated neuroblastoma cells in culture and increase levels of ubiquitin and beta-amyloid

1 reference

12 December 2020

Cyclooxygenase-2 inhibition prevents delayed death of CA1 hippocampal neurons following global ischemia

1 reference

12 December 2020

Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro.

1 reference

12 December 2020

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain

1 reference

12 December 2020

Prostaglandins as putative neurotoxins in Alzheimer's disease

1 reference

12 December 2020

Prostaglandin E receptor subtypes in cultured rat microglia and their role in reducing lipopolysaccharide-induced interleukin-1beta production

1 reference

12 December 2020

Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor

1 reference

12 December 2020

Molecular cloning, chromosome mapping and characterization of the mouse CRTH2 gene, a putative member of the leukocyte chemoattractant receptor family

1 reference

12 December 2020

10.1523/JNEUROSCI.4485-03.2004

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715958%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14715958%20AND%20SRC:MED&resulttype=core&format=json

17 November 2019

PubMed publication ID

14715958

1 reference