(Q44795441)

6 December 2017

Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events (English)

1 reference

6 December 2017

1 reference

Jie Han

1

1 reference

6 December 2017

Leslie A Goldstein

2

1 reference

6 December 2017

Brian R Gastman

3

1 reference

6 December 2017

Christopher J Froelich

4

1 reference

6 December 2017

Xiao-Ming Yin

5

1 reference

6 December 2017

Hannah Rabinowich

6

1 reference

6 December 2017

language of work or name

English

0 references

publication date

10 March 2004

1 reference

Journal of Biological Chemistry

6 December 2017

10

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

6 December 2017

279

1 reference

6 December 2017

22020-22029

1 reference

6 December 2017

21

1 reference

Cytotoxic T lymphocytes: all roads lead to death

6 December 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Mitochondria at the heart of the cytotoxic attack

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B-mediated apoptosis--the elephant and the blind men?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Caspase activation by granzyme B is indirect, and caspase autoprocessing requires the release of proapoptotic mitochondrial factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Myeloid cell factor-1 is a critical survival factor for multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Analysis of the membrane potential of rat- and mouse-liver mitochondria by flow cytometry and possible applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Regulated targeting of BAX to mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

BAX frameshift mutations in cell lines derived from human haemopoietic malignancies are associated with resistance to apoptosis and microsatellite instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

BCL-2 family members and the mitochondria in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Activation of mitochondrial voltage-dependent anion channel by apro-apoptotic BH3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

Modulation of cell death by Bcl-XL through caspase interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M313234200

21 January 2018

Identifiers

DOI

10.1074/JBC.M313234200

1 reference

6 December 2017

1 reference