(Q44883814)

English

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

7 December 2017

Common polymorphisms in the genes regulating the early insulin signalling pathway: effects on weight change and the conversion from impaired glucose tolerance to Type 2 diabetes. The Finnish Diabetes Prevention Study (English)

1 reference

Europe PubMed Central

7 December 2017

0 references

type 2 diabetes

1 reference

based on heuristic

inferred from title

Jaana Lindström

object named as

J Lindström

3

0 references

Jussi Pihlajamäki

object named as

J Pihlajamäki

2

0 references

Finnish Diabetes Prevention Study Group

12

object named as

Finnish Diabetes Prevention Study Group

1 reference

Europe PubMed Central

7 December 2017

11

object named as

M Laakso

1 reference

Europe PubMed Central

7 December 2017

Jaakko Tuomilehto

9

object named as

J Tuomilehto

1 reference

Europe PubMed Central

7 December 2017

4

object named as

J Eriksson

1 reference

Europe PubMed Central

7 December 2017

Sirkka Keinänen-Kiukaanniemi

8

object named as

S Keinänen-Kiukaanniemi

1 reference

Europe PubMed Central

7 December 2017

author name string

O Laukkanen

1

1 reference

Europe PubMed Central

7 December 2017

T T Valle

5

1 reference

Europe PubMed Central

7 December 2017

H Hämäläinen

6

1 reference

Europe PubMed Central

7 December 2017

P Ilanne-Parikka

7

1 reference

Europe PubMed Central

7 December 2017

M Uusitupa

10

1 reference

Europe PubMed Central

7 December 2017

publication date

1 May 2004

1 reference

Europe PubMed Central

7 December 2017

1 reference

Europe PubMed Central

7 December 2017

47

1 reference

Europe PubMed Central

7 December 2017

871-877

1 reference

Europe PubMed Central

7 December 2017

5

1 reference

Europe PubMed Central

7 December 2017

https://scigraph.springernature.com/pub.10.1007/s00125-004-1395-6

0 references

Cloning of human p55 gamma, a regulatory subunit of phosphatidylinositol 3-kinase, by a yeast two-hybrid library screen with the insulin-like growth factor-I receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Gly972-->Arg amino acid polymorphism in IRS-1 impairs insulin secretion in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes mellitus. Report of a WHO Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prevalent Gly1057Asp polymorphism in the insulin receptor substrate-2 gene is not associated with impaired insulin secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor substrate-1 variants in non-insulin-dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose transporters and insulin action--implications for insulin resistance and diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic effects of the Gly1057Asp polymorphism in IRS-2 and interactions with obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of the Pro12Ala polymorphism in the PPAR-gamma2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common amino acid polymorphism in insulin receptor substrate-1 causes impaired insulin signaling. Evidence from transfection studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased insulin sensitivity and hypoglycaemia in mice lacking the p85 alpha subunit of phosphoinositide 3-kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin secretory function is impaired in isolated human islets carrying the Gly(972)-->Arg IRS-1 polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of Type II diabetes in subjects with impaired glucose tolerance: the Diabetes Prevention Study (DPS) in Finland. Study design and 1-year interim report on the feasibility of the lifestyle intervention programme.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin gene VNTR is associated with fasting insulin levels and development of juvenile obesity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin resistance as the core defect in type 2 diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo studies of a naturally occurring variant of the human p85alpha regulatory subunit of the phosphoinositide 3-kinase: inhibition of protein kinase B and relationships with type 2 diabetes, insulin secretion, glucose disappearance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin signaling pathways in time and space.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IRS proteins and beta-cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85alpha): preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The insulin gene VNTR, type 2 diabetes and birth weight.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular genetics of non-insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism (K121Q) of the human glycoprotein PC-1 gene coding region is strongly associated with insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between the G1057D variant of IRS-2 and overweight in the pathogenesis of type 2 diabetes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15127203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00125-004-1395-6

1 reference

Europe PubMed Central

7 December 2017

1 reference

Europe PubMed Central

7 December 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44883814&oldid=2055140407"