(Q45070129)

9 December 2017

title

Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination (English)

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9 December 2017

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1 reference

Sheila R Plant

1

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9 December 2017

Heather A Arnett

series ordinal

2

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9 December 2017

Jenny P-Y Ting

series ordinal

3

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9 December 2017

publication date

1 January 2005

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9 December 2017

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9 December 2017

volume

49

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9 December 2017

issue

1

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9 December 2017

page(s)

1-14

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Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.

9 December 2017

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Onset of multiple sclerosis associated with anti-TNF therapy

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Increased MRI activity and immune activation in two multiple sclerosis patients treated with the monoclonal anti-tumor necrosis factor antibody cA2.

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Complementation of lymphotoxin alpha knockout mice with tumor necrosis factor-expressing transgenes rectifies defective splenic structure and function

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7 January 2021

TNF alpha promotes proliferation of oligodendrocyte progenitors and remyelination

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7 January 2021

Functional Genomic Analysis of Remyelination Reveals Importance of Inflammation in Oligodendrocyte Regeneration

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7 January 2021

Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins

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7 January 2021

Integrating anti-tumor necrosis factor therapy in inflammatory bowel disease: current and future perspectives

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7 January 2021

Differential effects of TNF and LTalpha in the host defense against M. bovis BCG

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7 January 2021

Apoptosis of oligodendrocytes in secondary cultures from neonatal rat brains

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7 January 2021

Antibodies to lymphotoxin alpha (LT alpha) and LT beta recognize different glial cell types in the central nervous system.

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7 January 2021

A lymphotoxin-beta-specific receptor

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7 January 2021

Are astrocytes central players in the pathophysiology of multiple sclerosis?

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7 January 2021

Immune function of astrocytes

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7 January 2021

TNF-alpha and -beta gene polymorphisms in multiple sclerosis: a highly significant role for determinants in the first intron of the TNF-beta gene.

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7 January 2021

Insights into programmed cell death through structural biology

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7 January 2021

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

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7 January 2021

Development and maturation of secondary lymphoid tissues.

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7 January 2021

Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice

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7 January 2021

Cytokines and antibodies in myelin oligodendrocyte glycoprotein-induced experimental allergic encephalomyelitis

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7 January 2021

Cellular localization and expression patterns of interleukin-10, interleukin-4, and their receptors in multiple sclerosis lesions

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7 January 2021

TNF-induced death of adult human oligodendrocytes is mediated by c-jun NH2-terminal kinase-3.

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7 January 2021

Uncoupling the proinflammatory from the immunosuppressive properties of tumor necrosis factor (TNF) at the p55 TNF receptor level: implications for pathogenesis and therapy of autoimmune demyelination

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7 January 2021

TNF-alpha receptor fusion protein prevents experimental auto-immune encephalomyelitis and demyelination in Lewis rats: an overview

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7 January 2021

Insulin-like growth factor I gene expression is induced in astrocytes during experimental demyelination

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7 January 2021

Membrane lymphotoxin is required for resistance to Theiler's virus infection.

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7 January 2021

The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis

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7 January 2021

TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

The role of TNFalpha and lymphotoxin in demyelinating disease

1 reference

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7 January 2021

The TNF and TNF receptor superfamilies: integrating mammalian biology

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7 January 2021

Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination

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7 January 2021

The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system.

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7 January 2021

Multiple sclerosis: the proinflammatory cytokines lymphotoxin-alpha and tumour necrosis factor-alpha are upregulated in cerebrospinal fluid mononuclear cells

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7 January 2021

Multiple roles for tumor necrosis factor-alpha and lymphotoxin alpha/beta in immunity and autoimmunity

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7 January 2021

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Distinct roles of the two tumor necrosis factor (TNF) receptors in modulating TNF and lymphotoxin alpha effects

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Gene expression in brain during cuprizone-induced demyelination and remyelination

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Augmented expression of tumour necrosis factor-alpha and lymphotoxin in mononuclear cells in multiple sclerosis and optic neuritis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Involvement of de novo ceramide biosynthesis in lymphotoxin-induced oligodendrocyte death

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Cytokine mRNA levels in mononuclear blood cells from patients with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Demyelinating and neurologic events reported in association with tumor necrosis factor alpha antagonism: by what mechanisms could tumor necrosis factor alpha antagonists improve rheumatoid arthritis but exacerbate multiple sclerosis?

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Challenging cytokine redundancy: inflammatory cell movement and clinical course of experimental autoimmune encephalomyelitis are normal in lymphotoxin-deficient, but not tumor necrosis factor-deficient, mice

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

A critical role for lymphotoxin in experimental allergic encephalomyelitis

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Rapid upregulation of the Pi isoform of glutathione-S-transferase in mouse brains after withdrawal of the neurotoxicant, cuprizone

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

https://api.crossref.org/works/10.1002%2FGLIA.20089

1 reference

7 January 2021

Tumor necrosis factor signaling.

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

In vitro evidence for a dual role of tumor necrosis factor‐α in human immunodeficiency virus type 1 encephalopathy

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Cytokine mRNA expression in inflammatory multiple sclerosis lesions: detection by non-radioactive in situ hybridization

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Reactive astrocytes in chronic active lesions of multiple sclerosis express co-stimulatory molecules B7-1 and B7-2

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.20089

7 January 2021

Identifiers

DOI

10.1002/GLIA.20089

1 reference

9 December 2017

1 reference