(Q45099758)

9 December 2017

Reduced PTEN expression predicts relapse in patients with breast carcinoma treated by tamoxifen (English)

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9 December 2017

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Nael Shoman

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9 December 2017

Shannon Klassen

2

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9 December 2017

Andrew McFadden

3

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9 December 2017

Miķelis G Bickis

4

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9 December 2017

Emina Torlakovic

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9 December 2017

Rajni Chibbar

6

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9 December 2017

1 February 2005

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9 December 2017

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9 December 2017

18

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9 December 2017

250-259

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9 December 2017

2

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https://scigraph.springernature.com/pub.10.1038/modpathol.3800296

9 December 2017

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cites work

The Biology of Antihormone Failure in Breast Cancer

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Endocrine-resistant breast cancer: Underlying mechanisms and strategies for overcoming resistance

21 January 2018

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Acquired tamoxifen resistance in human breast cancer--potential mechanisms and clinical implications

21 January 2018

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21 January 2018

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

7 January 2021

Tamoxifen resistance in breast cancer: elucidating mechanisms

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN/MMAC1/TEP1 in signal transduction and tumorigenesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Pten, a protean tumor suppressor

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Cellular survival: a play in three Akts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

The PTEN tumor suppressor is a negative modulator of androgen receptor transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Akt in prostate cancer: possible role in androgen-independence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Loss of expression of the PTEN gene protein product is associated with poor outcome in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Reduced expression of PTEN correlates with breast cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Reliability of immunohistochemical demonstration of oestrogen receptors in routine practice: interlaboratory variance in the sensitivity of detection and evaluation of scoring systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Nonparametric Estimation from Incomplete Observations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN: from pathology to biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Altered PTEN expression as a diagnostic marker for the earliest endometrial precancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Dysregulated PTEN-PKB and negative receptor status in human breast cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN: a tumour suppressor that functions as a phospholipid phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN induces apoptosis and cell cycle arrest through phosphoinositol-3-kinase/Akt-dependent and -independent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PI3K/Akt signalling pathway and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Modulation of PI3K/Akt pathway by E1a mediates sensitivity to cisplatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Eicosapentaenoic acid restores tamoxifen sensitivity in breast cancer cells with high Akt activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Deficiency of Pten accelerates mammary oncogenesis in MMTV-Wnt-1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Regulation of PTEN (phosphatase and tensin homolog deleted on chromosome 10) expression by estradiol and progesterone in human endometrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Regulation of Akt expression and phosphorylation by 17beta-estradiol in the rat uterus during estrous cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

PTEN, but not SHIP and SHIP2, suppresses the PI3K/Akt pathway and induces growth inhibition and apoptosis of myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

AKT inhibition is associated with chemosensitisation in the pancreatic cancer cell line MIA-PaCa-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Regulation of cell migration by the C2 domain of the tumor suppressor PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

Inactivation of the PTEN gene protein product is associated with the invasiveness and metastasis, but not angiogenesis, of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

7 January 2021

PTEN/MMAC1 in malignant melanoma and its importance for tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

7 January 2021

Allelic loss of the PTEN region (10q23) in breast carcinomas of poor pathophenotype

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

7 January 2021

Novel PTEN mutations in patients with Cowden disease: absence of clear genotype-phenotype correlations

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

7 January 2021

PI3 kinase blockade by Ad-PTEN inhibits invasion and induces apoptosis in RGP and metastatic melanoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FMODPATHOL.3800296

7 January 2021

10.1038/MODPATHOL.3800296

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9 December 2017

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1 reference