(Q45204273)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15621996%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

title

Treatment with simvastatin suppresses the development of experimental abdominal aortic aneurysms in normal and hypercholesterolemic mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15621996%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

0 references

1 reference

Eric F Steinmetz

1

1 reference

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6 January 2020

Celine Buckley

2

1 reference

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6 January 2020

Murray L Shames

3

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6 January 2020

Terri L Ennis

4

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6 January 2020

Sarah J Vanvickle-Chavez

5

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6 January 2020

Dongli Mao

6

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6 January 2020

Lee A Goeddel

7

1 reference

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6 January 2020

Cherady J Hawkins

8

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6 January 2020

Robert W Thompson

9

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6 January 2020

language of work or name

English

0 references

publication date

1 January 2005

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6 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15621996%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

volume

241

1 reference

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6 January 2020

issue

1

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6 January 2020

page(s)

92-101

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15621996%20AND%20SRC:MED&resulttype=core&format=json

Effects of hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin on smooth muscle cell proliferation in vitro and neointimal formation in vivo after vascular injury

6 January 2020

cites work

1 reference

12 December 2020

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

1 reference

12 December 2020

HMG CoA reductase inhibitors reduce plasminogen activator inhibitor-1 expression by human vascular smooth muscle and endothelial cells

1 reference

12 December 2020

Risk factors for abdominal aortic aneurysm: results of a case-control study

1 reference

12 December 2020

Hydroxymethylglutaryl coenzyme A reductase inhibitors modify the inflammatory response of human macrophages and endothelial cells infected with Chlamydia pneumoniae

1 reference

12 December 2020

Non-lipid-related effects of statins

1 reference

12 December 2020

The aneurysm detection and management study screening program: validation cohort and final results. Aneurysm Detection and Management Veterans Affairs Cooperative Study Investigators

1 reference

12 December 2020

Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

1 reference

12 December 2020

Accelerated replicative senescence of medial smooth muscle cells derived from abdominal aortic aneurysms compared to the adjacent inferior mesenteric artery

1 reference

12 December 2020

Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of ras isoprenylation

1 reference

12 December 2020

Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits urokinase/urokinase-receptor expression and MMP-9 secretion by peripheral blood monocytes--a possible protective mechanism against atherothrombosis

1 reference

12 December 2020

HMG-CoA reductase inhibition improves endothelial cell function and inhibits smooth muscle cell proliferation in human saphenous veins

1 reference

12 December 2020

Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering

1 reference

12 December 2020

Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and Rac1 GTPase.

1 reference

12 December 2020

Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization

1 reference

12 December 2020

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits

1 reference

12 December 2020

Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes: the MIRACL study: a randomized controlled trial

1 reference

12 December 2020

Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors

1 reference

12 December 2020

Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation.

1 reference

12 December 2020

Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study

1 reference

12 December 2020

Simvastatin inhibits expression of tissue factor in advanced atherosclerotic lesions of apolipoprotein E deficient mice independently of lipid lowering: potential role of simvastatin-mediated inhibition of Egr-1 expression and activation

1 reference

12 December 2020

Transient exposure to elastase induces mouse aortic wall smooth muscle cell production of MCP-1 and RANTES during development of experimental aortic aneurysm.

1 reference

12 December 2020

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro

1 reference

12 December 2020

Ten-year mortality from cardiovascular disease in relation to cholesterol level among men with and without preexisting cardiovascular disease

1 reference

12 December 2020

Atherosclerotic plaque rupture and thrombosis. Evolving concepts

1 reference

12 December 2020

Aneurysm formation in experimental atherosclerosis: relationship to plaque evolution

1 reference

12 December 2020

Aortic aneurysms and atherosclerosis

1 reference

12 December 2020

Aneurysmal enlargement of the aorta during regression of experimental atherosclerosis

1 reference

12 December 2020

Lipid lowering and plaque regression. New insights into prevention of plaque disruption and clinical events in coronary disease

1 reference

12 December 2020

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree

1 reference

12 December 2020

The emerging concept of vascular remodeling

1 reference

12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

Types of change in coronary stenosis severity and their relative importance in overall progression and regression of coronary disease. Observations from the FATS Trial. Familial Atherosclerosis Treatment Study

1 reference

12 December 2020

In vivo cholesterol kinetics in apolipoprotein E-deficient and control mice

1 reference

12 December 2020

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

1 reference

12 December 2020

Doxycycline inhibition of aneurysmal degeneration in an elastase-induced rat model of abdominal aortic aneurysm: preservation of aortic elastin associated with suppressed production of 92 kD gelatinase

1 reference

12 December 2020

Indomethacin prevents elastase-induced abdominal aortic aneurysms in the rat

1 reference

12 December 2020

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

1 reference

12 December 2020

Basic science of abdominal aortic aneurysms: emerging therapeutic strategies for an unresolved clinical problem

1 reference

12 December 2020

Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms.

1 reference

12 December 2020

Inhibitory effect of fluvastatin, an HMG-CoA reductase inhibitor, on the expression of adhesion molecules on human monocyte cell line

1 reference

12 December 2020

HMG-CoA reductase inhibitors suppress macrophage growth induced by oxidized low density lipoprotein

1 reference

12 December 2020

Experimental abdominal aortic aneurysms in mice lacking expression of inducible nitric oxide synthase

1 reference

12 December 2020

Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors

1 reference

12 December 2020

Abdominal aortic aneurysms: basic mechanisms and clinical implications

1 reference

12 December 2020

Anti-atherosclerotic effect of simvastatin depends on the presence of apolipoprotein E.

1 reference

12 December 2020

Doxycycline in patients with abdominal aortic aneurysms and in mice: comparison of serum levels and effect on aneurysm growth in mice

1 reference

12 December 2020

Simvastatin inhibits human saphenous vein neointima formation via inhibition of smooth muscle cell proliferation and migration

1 reference

12 December 2020

Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages

1 reference

12 December 2020

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

1 reference

12 December 2020

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1 reference

12 December 2020

HMG-CoA reductase inhibitors reduce MMP-9 secretion by macrophages

1 reference

12 December 2020

HMG-CoA reductase inhibition by atorvastatin reduces neointimal inflammation in a rabbit model of atherosclerosis

1 reference

12 December 2020

The matrix metalloproteinase inhibitor BB-94 limits expansion of experimental abdominal aortic aneurysms

1 reference

12 December 2020

3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors attenuate vascular smooth muscle proliferation by preventing rho GTPase-induced down-regulation of p27(Kip1)

1 reference

12 December 2020

A 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall

1 reference

12 December 2020

Isoprenoids as mediators of the biological effects of statins

1 reference

12 December 2020

Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms

1 reference

12 December 2020

Beyond lipid lowering: the role of statins in vascular protection

1 reference

12 December 2020

Simvastatin promotes atherosclerotic plaque stability in apoE-deficient mice independently of lipid lowering

1 reference

12 December 2020

Modulation of the inflammatory process by statins

1 reference

12 December 2020

Statins inhibit secretion of metalloproteinases-1, -2, -3, and -9 from vascular smooth muscle cells and macrophages

1 reference

12 December 2020

10.1097/01.SLA.0000150258.36236.E0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15621996%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference