(Q45259201)

11 December 2017

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations (English)

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11 December 2017

3

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11 December 2017

5

Alan R Fersht

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11 December 2017

1

Andreas C Joerger

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11 December 2017

Hwee Ching Ang

2

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PubMed ID

15703170

11 December 2017

Caroline M Blair

series ordinal

4

1 reference

PubMed ID

15703170

11 December 2017

language of work or name

English

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publication date

9 February 2005

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Journal of Biological Chemistry

11 December 2017

8

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based on heuristic

inferred from page(s)

published in

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11 December 2017

280

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11 December 2017

16030-16037

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11 December 2017

16

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11 December 2017

Surfing the p53 network

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https://api.crossref.org/works/10.1074%2FJBC.M500179200

Regulation and function of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Live or let die: the cell's response to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Thermodynamic stability of wild-type and mutant p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Quantitative analysis of residual folding and DNA binding in mutant p53 core domain: definition of mutant states for rescue in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

A global suppressor motif for p53 cancer mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Mechanism of rescue of common p53 cancer mutations by second-site suppressor mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Semirational design of active tumor suppressor p53 DNA binding domain with enhanced stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Crystal structure of a superstable mutant of human p53 core domain. Insights into the mechanism of rescuing oncogenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Hot-spot mutants of p53 core domain evince characteristic local structural changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Cooperative binding of tetrameric p53 to DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Raster3D: photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

The IARC TP53 database: new online mutation analysis and recommendations to users

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide: implications for "mutant conformation".

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Binding of Rad51 and other peptide sequences to a promiscuous, highly electrostatic binding site in p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Distinct residues of human p53 implicated in binding to DNA, simian virus 40 large T antigen, 53BP1, and 53BP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

53BP1, a mediator of the DNA damage checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M500179200

21 January 2018

Identifiers

DOI

10.1074/JBC.M500179200

1 reference

11 December 2017

1 reference

PubMed ID

15703170