(Q45269926)

English

The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis.

scientific article

The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis

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2 October 2019

The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis (English)

1 reference

Europe PubMed Central

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2 October 2019

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1 reference

based on heuristic

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1 reference

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author name string

Allegra CJ

1

1 reference

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2 October 2019

Fine RL

2

1 reference

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2 October 2019

Drake JC

3

1 reference

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2 October 2019

Chabner BA

4

1 reference

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2 October 2019

C J Allegra

1

0 references

R L Fine

2

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J C Drake

3

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B A Chabner

4

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language of work or name

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publication date

1 May 1986

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2 October 2019

May 1986

0 references

Journal of Biological Chemistry

1 reference

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2 October 2019

261

1 reference

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2 October 2019

6478-6485

1 reference

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2 October 2019

14

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2 October 2019

Folylpoly-gamma-glutamates as cosubstrates of 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Polygammaglutamyl metabolites of methotrexate.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Extracellular recovery of methotrexate-polyglutamates following efflux from L1210 leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Methotrexate polyglutamate synthesis by cultured human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Human thymidylate synthetase--III. Effects of methotrexate and folate analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Response of methylenetetrahydrofolate levels to methotrexate in Krebs ascites cells

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The reaction of tetrahydropteroylglutamic acid and related hydropteridines with formaldehyde

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

A simple procedure for the synthesis of high specific activity tritiated (6S)-5-formyltetrahydrofolate

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

High-pressure liquid chromatography separation and determination of rat liver folates

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of de novo purine synthesis inhibitors on 5-fluorouracil metabolism and cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of folate cofactor levels in tissues using high-performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Investigations of tissue folates in normal and malignant tissues

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Direct transfer of one-carbon units in the transformylations of de novo purine biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of various antileukemic compounds on the production of a diazotizable amine (probably 4-amino-5-imidazolecarboxamide) by Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Aminopterin inhibition in Aerobacter aerogenes; alanine and valine accumulation during the inhibition and their utilization on recovery

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Interactions of pig liver methylenetetrahydrofolate reductase with methylenetetrahydropteroylpolyglutamate substrates and with dihydropteroylpolyglutamate inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0021-9258%2819%2984587-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0021-9258(19)84587-8

0 references

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:3700401%20AND%20SRC:MED&resulttype=core&format=json

2 October 2019

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