(Q45963155)

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Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging. (English)

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

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functional neuroimaging

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Joseph H Callicott

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Daniel R. Weinberger

13

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Daniel R Weinberger

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18 December 2017

8

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Ina Giegling

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18 December 2017

9

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Dan Rujescu

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18 December 2017

http://europepmc.org/abstract/MED/20084519

10

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David St Clair

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Kristin K Nicodemus

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Kristin K Nicodemus

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Pierandrea Muglia

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Pierandrea Muglia

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18 December 2017

http://europepmc.org/abstract/MED/20084519

4

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Augustin Luna

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Radhakrishna Vakkalanka

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Radhakrishna Vakkalanka

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Barbara K Lipska

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Barbara K Lipska

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18 December 2017

http://europepmc.org/abstract/MED/20084519

author name string

Rachel G Higier

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Devon C Nixon

5

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/20084519

Yin Yao Shugart

12

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18 December 2017

http://europepmc.org/abstract/MED/20084519

publication date

1 April 2010

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/20084519

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

127

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

4

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Europe PubMed Central

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18 December 2017

http://europepmc.org/abstract/MED/20084519

441-452

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Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia.

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https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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DISC1-NDEL1/NUDEL protein interaction, an essential component for neurite outgrowth, is modulated by genetic variations of DISC1

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https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between the TRAX/DISC locus and both bipolar disorder and schizophrenia in the Scottish population

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https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Citron, a Rho-target, interacts with PSD-95/SAP-90 at glutamatergic synapses in the thalamus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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The genetics and biology of DISC1--an emerging role in psychosis and cognition

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https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

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https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.

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https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficiency and power in genetic association studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association study of polymorphisms in the 5' upstream region of human DISC1 gene with schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genome-wide investigation of SNPs and CNVs in schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantifying the heritability of task-related brain activation and performance during the N-back working memory task: a twin fMRI study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association analysis of schizophrenia on 18 genes involved in neuronal migration: MDGA1 as a new susceptibility gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

False positives in imaging genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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Physiological characteristics of capacity constraints in working memory as revealed by functional MRI.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association within a family of a balanced autosomal translocation with major mental illness

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular levels of the LIS1 protein correlate with clinical and neuroradiological findings in patients with classical lissencephaly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of DISC1 binding partners is reduced in schizophrenia and associated with DISC1 SNPs

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DISC1 (Disrupted-In-Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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No association between the NDE1 gene and schizophrenia in the Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association study of the DISC1/TRAX locus with schizophrenia in a Japanese population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

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Failure to confirm the association between the FEZ1 gene and schizophrenia in a Japanese population

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complexity and power in case-control association studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant support for DAO as a schizophrenia susceptibility locus: examination of five genes putatively associated with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predictor correlation impacts machine learning algorithms: implications for genomic studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral phenotypes of Disc1 missense mutations in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of high risk DISC1 structural variants with a 2% attributable risk for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of disrupted-in-schizophrenia (DISC1) in bipolar disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single nucleotide polymorphism fine mapping study of chromosome 1q42.1 reveals the vulnerability genes for schizophrenia, GNPAT and DISC1: Association with impairment of sustained attention.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence of association between bipolar disorder and Citron on chromosome 12q24.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strong association of de novo copy number mutations with sporadic schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence analysis using logic regression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association analysis of FEZ1 variants with schizophrenia in Japanese cohorts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intermediate phenotypes and genetic mechanisms of psychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stability of variable importance scores and rankings using statistical learning tools on single-nucleotide polymorphisms and risk factors involved in gene x gene and gene x environment interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disrupted in Schizophrenia 1 and Nudel form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic association between schizophrenia and the DISC1 gene in the Scottish population.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of two novel genes by a translocation co-segregating with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The FEZ1 gene shows no association to schizophrenia in Caucasian or African American populations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative risk of attention deficits in siblings of patients with schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifying interacting SNPs using Monte Carlo logic regression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Asymptotic power calculations: description, examples, computer code

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling PAF Signaling to Dynein Regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling PAF signaling to dynein regulation: structure of LIS1 in complex with PAF-acetylhydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/20084519

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S00439-009-0782-Y

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

18 December 2017

http://europepmc.org/abstract/MED/20084519

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