(Q45991206)

18 December 2017

title

Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1. (English)

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18 December 2017

author name string

K Tanaka

series ordinal

1

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18 December 2017

P Russell

series ordinal

2

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18 December 2017

publication date

1 November 2001

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18 December 2017

published in

Nature Cell Biology

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18 December 2017

volume

3

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18 December 2017

page(s)

966-972

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18 December 2017

issue

11

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18 December 2017

https://scigraph.springernature.com/pub.10.1038/ncb1101-966

exact match

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Replication checkpoint enforced by kinases Cds1 and Chk1.

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Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

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Analysis of Rad3 and Chk1 protein kinases defines different checkpoint responses.

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Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast

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Cdc25 inhibited in vivo and in vitro by checkpoint kinases Cds1 and Chk1

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Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1

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Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

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Identifiers

DOI

10.1038/NCB1101-966

1 reference

18 December 2017

Dimensions Publication ID

0 references

1 reference

18 December 2017