(Q46006991)

18 December 2017

title

PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity. (English)

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18 December 2017

author name string

Bin Liu

1

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18 December 2017

Sheldon Mink

2

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18 December 2017

Kelly A Wong

3

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18 December 2017

Natalie Stein

4

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18 December 2017

Crescent Getman

5

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18 December 2017

Paul W Dempsey

6

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18 December 2017

Hong Wu

7

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18 December 2017

Ke Shuai

8

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18 December 2017

language of work or name

English

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publication date

15 August 2004

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18 December 2017

published in

Nature Immunology

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18 December 2017

volume

5

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18 December 2017

page(s)

891-898

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18 December 2017

issue

9

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18 December 2017

How cells respond to interferons

cites work

1 reference

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

1 reference

Stats: transcriptional control and biological impact

21 January 2018

1 reference

Regulation of JAK-STAT signalling in the immune system

21 January 2018

1 reference

Negative regulators of cytokine signal transduction

21 January 2018

1 reference

Identification of a nuclear Stat1 protein tyrosine phosphatase

21 January 2018

1 reference

Inhibition of Stat1-mediated gene activation by PIAS1

21 January 2018

1 reference

Specific inhibition of Stat3 signal transduction by PIAS3

21 January 2018

1 reference

PIASx is a transcriptional co-repressor of signal transducer and activator of transcription 4

21 January 2018

1 reference

A transcriptional corepressor of Stat1 with an essential LXXLL signature motif

21 January 2018

1 reference

Biologic consequences of Stat1-independent IFN signaling.

21 January 2018

1 reference

Stat1-independent regulation of gene expression in response to IFN-gamma

21 January 2018

1 reference

Stat1-dependent and -independent pathways in IFN-gamma-dependent signaling

21 January 2018

1 reference

The STAT3 isoforms alpha and beta have unique and specific functions

21 January 2018

1 reference

JAK/STAT signaling by cytokine receptors

21 January 2018

1 reference

Activation of transcription by IFN-gamma: tyrosine phosphorylation of a 91-kD DNA binding protein

21 January 2018

1 reference

Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds

21 January 2018

1 reference

Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity

21 January 2018

1 reference

IFNs and STATs in innate immunity to microorganisms

21 January 2018

1 reference

Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus

21 January 2018

1 reference

IRF3 mediates a TLR3/TLR4-specific antiviral gene program

21 January 2018

1 reference

Transcription program of murine gammaherpesvirus 68

21 January 2018

1 reference

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

21 January 2018

1 reference

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

21 January 2018

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Interferon gamma receptor deficient mice are resistant to endotoxic shock

21 January 2018

1 reference

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

21 January 2018

1 reference

Involvement of PIAS1 in the sumoylation of tumor suppressor p53

21 January 2018

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Activation of p53 by protein inhibitor of activated Stat1 (PIAS1)

21 January 2018

1 reference

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

21 January 2018

1 reference

An E3-like factor that promotes SUMO conjugation to the yeast septins

21 January 2018

1 reference

Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3

21 January 2018

1 reference

SUMO modification of STAT1 and its role in PIAS-mediated inhibition of gene activation

21 January 2018

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PIAS proteins promote SUMO-1 conjugation to STAT1

21 January 2018

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Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

21 January 2018

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Rta of murine gammaherpesvirus 68 reactivates the complete lytic cycle from latency.

21 January 2018

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Suppressors of cytokine signalling (SOCS) in the immune system

21 January 2018

1 reference

7 January 2021

Tyrosine phosphorylated p91 binds to a single element in the ISGF2/IRF-1 promoter to mediate induction by IFN alpha and IFN gamma, and is likely to autoregulate the p91 gene.

1 reference

7 January 2021

SOCS1/JAB is a negative regulator of LPS-induced macrophage activation

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7 January 2021

SOCS-1 participates in negative regulation of LPS responses

1 reference

7 January 2021

Identifiers

DOI

10.1038/NI1104

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18 December 2017

PubMed ID

15311277

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18 December 2017