(Q46055131)

19 December 2017

review article

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title

The caspase-RB connection in cell death (English)

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19 December 2017

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X Tan

1

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19 December 2017

J Y Wang

series ordinal

2

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19 December 2017

publication date

1 March 1998

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19 December 2017

published in

Trends in Cell Biology

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19 December 2017

volume

8

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19 December 2017

page(s)

116-120

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19 December 2017

issue

3

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19 December 2017

Caspases: killer proteases

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7 January 2021

Death substrates come alive

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Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

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Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

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Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

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Cleavage of PITSLRE kinases by ICE/CASP-1 and CPP32/CASP-3 during apoptosis induced by tumor necrosis factor

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7 January 2021

Identification of the MDM2 oncoprotein as a substrate for CPP32-like apoptotic proteases

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7 January 2021

Apoptosis is associated with cleavage of a 5 kDa fragment from RB which mimics dephosphorylation and modulates E2F binding

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Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.

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Degradation of retinoblastoma protein in tumor necrosis factor- and CD95-induced cell death.

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Specific cleavage of the large subunit of replication factor C in apoptosis is mediated by CPP32-like protease

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Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease

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Cleavage of the nuclear matrix protein NuMA during apoptosis

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Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis

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Lamin proteolysis facilitates nuclear events during apoptosis

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Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

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7 January 2021

Protease activation during apoptosis: death by a thousand cuts?

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The retinoblastoma protein and cell cycle control

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Speculations on the roles of RB1 in tissue-specific differentiation, tumor initiation, and tumor progression.

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Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation

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Effects of an Rb mutation in the mouse

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

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Requirement for a functional Rb-1 gene in murine development

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Life, death, and the pursuit of apoptosis.

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Targeted disruption of p107: functional overlap between p107 and Rb

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Retinoblastoma protein in growth suppression and death protection

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E2F-1 functions in mice to promote apoptosis and suppress proliferation

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Three distinct signalling responses by murine fibroblasts to genotoxic stress

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Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation

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Repression of p53-mediated transcription by MDM2: a dual mechanism

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mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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Identifiers

DOI

1 reference

19 December 2017

PubMed ID

9695821

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19 December 2017