(Q46174622)

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Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients

scientific article published on 29 September 2013

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Pharmacogenetic associations with plasma efavirenz concentrations and clinical correlates in a retrospective cohort of Ghanaian HIV-infected patients (English)

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

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9

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Richard Phillips

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Richard Phillips

5

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Fred Stephen Sarfo

1

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Fred S Sarfo

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

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Yuan Zhang

2

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Deirdre Egan

3

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Lambert A Tetteh

4

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

George Bedu-Addo

6

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Maame Anima Sarfo

7

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Saye Khoo

8

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

David R Chadwick

10

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Europe PubMed Central

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20 December 2017

http://europepmc.org/abstract/MED/24080498

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publication date

29 September 2013

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Europe PubMed Central

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20 December 2017

http://europepmc.org/abstract/MED/24080498

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9

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Journal of Antimicrobial Chemotherapy

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Europe PubMed Central

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20 December 2017

http://europepmc.org/abstract/MED/24080498

69

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20 December 2017

http://europepmc.org/abstract/MED/24080498

2

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

491-499

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Genetic variability of CYP2B6 in populations of African and Asian origin: allele frequencies, novel functional variants, and possible implications for anti-HIV therapy with efavirenz

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Correlates of efavirenz exposure in Chilean patients affected with human immunodeficiency virus reveals a novel association with a polymorphism in the constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

CYP2B6 (c.516G→T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Polymorphic CYP2B6: molecular mechanisms and emerging clinical significance

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIV-infected individuals.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Presence of the CYP2B6 516G> T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Genome-wide association study of plasma efavirenz pharmacokinetics in AIDS Clinical Trials Group protocols implicates several CYP2B6 variants

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Self-report measures of antiretroviral therapy adherence: A review with recommendations for HIV research and clinical management

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Self-Reported Adherence to Antiretroviral Therapy for HIV-1 Infection and Virologic Treatment Response

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKT372

21 January 2018

Identifiers

10.1093/JAC/DKT372

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/24080498

ResearchGate publication ID

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