(Q46327841)

21 December 2017

title

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization (English)

1 reference

21 December 2017

author

L. Mario Amzel

5

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21 December 2017

Christopher A Ross

6

object named as

Christopher A Ross

1 reference

21 December 2017

author name string

Michelle A Poirier

1

1 reference

21 December 2017

Huilin Li

2

1 reference

21 December 2017

Jed Macosko

3

1 reference

21 December 2017

Shuowei Cai

4

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21 December 2017

language of work or name

English

0 references

publication date

8 August 2002

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21 December 2017

Journal of Biological Chemistry

published in

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21 December 2017

volume

277

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21 December 2017

page(s)

41032-41037

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21 December 2017

issue

43

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21 December 2017

Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Toward an understanding of polyglutamine neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Glutamine repeats and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Trinucleotide repeat length instability and age of onset in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: implications for Huntington's disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

A bivalent Huntingtin binding peptide suppresses polyglutamine aggregation and pathogenesis in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Preparation of human cDNas encoding expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Isolation of a 40-kDa Huntingtin-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Wrapping of DNA around the E.coli RNA polymerase open promoter complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Solution structure of polyglutamine tracts in GST-polyglutamine fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Assembly of A beta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Inhibition of fibrillization and accumulation of prefibrillar oligomers in mixtures of human and mouse alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Nucleated conformational conversion and the replication of conformational information by a prion determinant

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Conformational Abs recognizing a generic amyloid fibril epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Nuclear inclusions in glutamine repeat disorders: are they pernicious, coincidental, or beneficial?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Role of zinc in the structure and toxic activity of botulinum neurotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M205809200

21 January 2018

Identifiers

DOI

10.1074/JBC.M205809200

1 reference

21 December 2017

release_3yg2pnxwyrfnrjipfcjrwhryau

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3yg2pnxwyrfnrjipfcjrwhryau

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

12171927

1 reference

21 December 2017