(Q46453472)

English

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels

scientific article published on 31 July 2008

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scholarly article

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

Cleavage in the {gamma}-subunit of the epithelial sodium channel (ENaC) plays an important role in the proteolytic activation of near-silent channels (English)

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

1 reference

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author name string

Alexei Diakov

1

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

Katarzyna Bera

2

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

Marianna Mokrushina

3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

Bettina Krueger

4

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

Christoph Korbmacher

5

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

language of work or name

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publication date

31 July 2008

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

number of pages

22

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Journal of Physiology

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

586

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Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

4587-4608

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

19

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

Surface expression of epithelial Na channel protein in rat kidney

1 reference

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26 August 2018

Preferential assembly of epithelial sodium channel (ENaC) subunits in Xenopus oocytes: role of furin-mediated endogenous proteolysis

1 reference

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26 August 2018

A segment of gamma ENaC mediates elastase activation of Na+ transport

1 reference

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26 August 2018

Sodium self-inhibition of human epithelial sodium channel: selectivity and affinity of the extracellular sodium sensing site.

1 reference

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26 August 2018

Indirect activation of the epithelial Na+ channel by trypsin

1 reference

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26 August 2018

Epithelial Na+ channels are fully activated by furin- and prostasin-dependent release of an inhibitory peptide from the gamma-subunit.

1 reference

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26 August 2018

A novel neutrophil elastase inhibitor prevents elastase activation and surface cleavage of the epithelial sodium channel expressed in Xenopus laevis oocytes.

1 reference

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26 August 2018

Regulation of ENaCs by proteases: An increasingly complex story.

1 reference

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26 August 2018

Inhibition of prostasin-induced ENaC activities by PN-1 and regulation of PN-1 expression by TGF-beta1 and aldosterone

1 reference

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26 August 2018

The epithelial Na+ channel is inhibited by a peptide derived from proteolytic processing of its alpha subunit.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

Regulation of maturation and processing of ENaC subunits in the rat kidney

1 reference

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26 August 2018

Activation of epithelial sodium channels by mouse channel activating proteases (mCAP) expressed in Xenopus oocytes requires catalytic activity of mCAP3 and mCAP2 but not mCAP1.

1 reference

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26 August 2018

Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage

1 reference

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26 August 2018

Stimulation of the epithelial sodium channel (ENaC) by cAMP involves putative ERK phosphorylation sites in the C termini of the channel's beta- and gamma-subunit

1 reference

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26 August 2018

Furin cleavage activates the epithelial Na+ channel by relieving Na+ self-inhibition.

1 reference

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26 August 2018

Stimulation of the epithelial sodium channel (ENaC) by the serum- and glucocorticoid-inducible kinase (Sgk) involves the PY motifs of the channel but is independent of sodium feedback inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

Urinary prostasin: a candidate marker of epithelial sodium channel activation in humans.

1 reference

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26 August 2018

The epithelial sodium channel: activation by membrane-bound serine proteases

1 reference

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26 August 2018

Proprotein convertase genes in Xenopus development

1 reference

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26 August 2018

Neutrophil elastase activates near-silent epithelial Na+ channels and increases airway epithelial Na+ transport.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

Biochemical characterization of prostasin, a channel activating protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

Distinct pools of epithelial sodium channels are expressed at the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

1 reference

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26 August 2018

Epithelial sodium channels are activated by furin-dependent proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

New concepts of the pathogenesis of cystic fibrosis lung disease

1 reference

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26 August 2018

Serine protease activation of near-silent epithelial Na+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2614049

26 August 2018

The gamma-subunit of ENaC is more important for channel surface expression than the beta-subunit

1 reference

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26 August 2018

Precursor processing by kex2/furin proteases

1 reference

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26 August 2018

Furin at the cutting edge: from protein traffic to embryogenesis and disease

1 reference

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26 August 2018

An external site controls closing of the epithelial Na+ channel ENaC.

1 reference

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26 August 2018

Synergistic activation of ENaC by three membrane-bound channel-activating serine proteases (mCAP1, mCAP2, and mCAP3) and serum- and glucocorticoid-regulated kinase (Sgk1) in Xenopus Oocytes

1 reference

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26 August 2018

Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

1 reference

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26 August 2018

Regulation of the epithelial sodium channel by N4WBP5A, a novel Nedd4/Nedd4-2-interacting protein

1 reference

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26 August 2018

Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel

1 reference

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26 August 2018

Cell-surface expression of the channel activating protease xCAP-1 is required for activation of ENaC in the Xenopus oocyte.

1 reference

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26 August 2018

Regulation of prostasin by aldosterone in the kidney.

1 reference

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26 August 2018

Epithelial sodium channel and the control of sodium balance: interaction between genetic and environmental factors

1 reference

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26 August 2018

Sulfonylurea receptors inhibit the epithelial sodium channel (ENaC) by reducing surface expression

1 reference

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26 August 2018

Activation of epithelial sodium channels by prostasin in Xenopus oocytes

1 reference

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26 August 2018

Conservation of pH sensitivity in the epithelial sodium channel (ENaC) with Liddle's syndrome mutation.

1 reference

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26 August 2018

Activation of the amiloride-sensitive epithelial sodium channel by the serine protease mCAP1 expressed in a mouse cortical collecting duct cell line

1 reference

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26 August 2018

Subunit composition determines the single channel kinetics of the epithelial sodium channel

1 reference

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26 August 2018

Protease modulation of the activity of the epithelial sodium channel expressed in Xenopus oocytes

1 reference

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26 August 2018

An epithelial serine protease activates the amiloride-sensitive sodium channel

1 reference

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Diversity of channels generated by different combinations of epithelial sodium channel subunits

1 reference

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26 August 2018

Epithelial sodium channels: function, structure, and regulation

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26 August 2018

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach

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Early death due to defective neonatal lung liquid clearance in alpha-ENaC-deficient mice.

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26 August 2018

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

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Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland

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A calcium-activated and nucleotide-sensitive nonselective cation channel in M-1 mouse cortical collecting duct cells

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Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

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Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes

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26 August 2018

Identifiers

10.1113/JPHYSIOL.2008.154435

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

0 references

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18669538

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