(Q46505331)

22 December 2017

title

The ruthenium(II)-arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53-JNK pathways (English)

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22 December 2017

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4

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22 December 2017

Paul Dyson

object named as

Paul J Dyson

5

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author name string

Soumya Chatterjee

1

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22 December 2017

Subhadip Kundu

2

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22 December 2017

Arindam Bhattacharyya

3

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22 December 2017

publication date

3 July 2008

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22 December 2017

Journal of Biological Inorganic Chemistry

published in

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22 December 2017

volume

13

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22 December 2017

page(s)

1149-1155

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22 December 2017

issue

7

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22 December 2017

https://scigraph.springernature.com/pub.10.1007/s00775-008-0400-9

exact match

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cites work

Enabling death by the Abl tyrosine kinase: mechanisms for nuclear shuttling of c-Abl in response to DNA damage

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Crossref

https://api.crossref.org/works/10.1007%2FS00775-008-0400-9

Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells.

21 January 2018

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From bench to bedside--preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A).

21 January 2018

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12 December 2020

Cellular effects of transferrin coordinated to.

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12 December 2020

Ruthenium (II)-derived organometallic compounds induce cytostatic and cytotoxic effects on mammalian cancer cell lines through p53-dependent and p53-independent mechanisms.

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12 December 2020

Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells

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12 December 2020

Mechanisms of cytochrome c release from mitochondria

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12 December 2020

Effects of hypoxia and transferrin on toxicity and DNA binding of ruthenium antitumor agents in hela cells

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12 December 2020

Antitumor activity of some ruthenium derivatives in human colon cancer cell lines in vitro

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12 December 2020

Metal-based antitumour drugs in the post genomic era.

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12 December 2020

Development of organometallic ruthenium-arene anticancer drugs that resist hydrolysis

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12 December 2020

A new cholescintigraphic agent: ruthenium-97-DISIDA.

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12 December 2020

JNK targets p53 ubiquitination and degradation in nonstressed cells

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12 December 2020

Tuning the hydrophobicity of ruthenium(II)-arene (RAPTA) drugs to modify uptake, biomolecular interactions and efficacy.

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12 December 2020

Investigation of the role of Bax, p21/Waf1 and p53 as determinants of cellular responses in HCT116 colorectal cancer cells exposed to the novel cytotoxic ruthenium(II) organometallic agent, RM175.

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12 December 2020

The p53 pathway: positive and negative feedback loops

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12 December 2020

Redox-active antineoplastic ruthenium complexes with indazole: correlation of in vitro potency and reduction potential

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12 December 2020

Interactions of antitumor metallodrugs with serum proteins: advances in characterization using modern analytical methodology.

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12 December 2020

Prodigiosin induces caspase-9 and caspase-8 activation and cytochrome C release in Jurkat T cells

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12 December 2020

Correlation of p53 and bcl-2 expression with vascular endothelial growth factor (VEGF), microvessel density (MVD) and clinico-pathological features in colon cancer.

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12 December 2020

Platinum group metallodrug-protein binding studies by capillary electrophoresis - inductively coupled plasma-mass spectrometry: a further insight into the reactivity of a novel antitumor ruthenium(III) complex toward human serum proteins.

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12 December 2020

In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

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12 December 2020

In vitro and in vivo evaluation of ruthenium(II)-arene PTA complexes

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12 December 2020

Long-patch base excision repair of apurinic/apyrimidinic site DNA is decreased in mouse embryonic fibroblast cell lines treated with plumbagin: involvement of cyclin-dependent kinase inhibitor p21Waf-1/Cip-1.

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12 December 2020

Senescence-like changes induced by expression of p21(waf1/Cip1) in NIH3T3 cell line

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12 December 2020

Regulation of Bax translocation through phosphorylation at Ser-70 of Bcl-2 by MAP kinase in NO-induced neuronal apoptosis.

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12 December 2020

A Phase I and pharmacological study with imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a novel ruthenium anticancer agent.

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12 December 2020

The binding properties of two antitumor ruthenium(III) complexes to apotransferrin

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12 December 2020

Is there life after technetium: what is the potential for developing new broad-based radionuclides?

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12 December 2020

Role of JNK activation in apoptosis: a double-edged sword

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12 December 2020

Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells.

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12 December 2020

Ruthenium-based compounds and tumour growth control (review).

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12 December 2020

A comparative study of adduct formation between the anticancer ruthenium(III) compound HInd trans-[RuCl4(Ind)2] and serum proteins.

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12 December 2020

The biochemistry of apoptosis

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12 December 2020

A calmodulin-binding site on cyclin E mediates Ca2+-sensitive G1/s transitions in vascular smooth muscle cells

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12 December 2020

Efficacy of new ruthenium complexes against chemically induced autochthonous colorectal carcinoma in rats

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12 December 2020

New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?

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12 December 2020

Regulation of the G2/M transition by p53.

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12 December 2020

Antitumour metal compounds: more than theme and variations

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12 December 2020

Redox behavior of tumor-inhibiting ruthenium(iii) complexes and effects of physiological reductants on their binding to GMP

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12 December 2020

Current status of platinum-based antitumor drugs

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12 December 2020

Interaction of tetra-azaphenanthrene ruthenium complexes with DNA and oligonucleotides. A photophysical and photochemical investigation

1 reference

12 December 2020

Antineoplastic activity of three ruthenium derivatives against chemically induced colorectal carcinoma in rats

1 reference

12 December 2020

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

1 reference

12 December 2020

10.1007/S00775-008-0400-9

Identifiers

DOI

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22 December 2017

PubMed ID

18597125

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22 December 2017