(Q46526697)

English

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe

scientific article published on 5 December 2007

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scholarly article

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

High prevalence of the CYP2B6 516G-->T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe (English)

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

0 references

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

Collen Masimirembwa

7

object named as

Collen Masimirembwa

1 reference

Europe PubMed Central

22 December 2017

author name string

Christopher Nyakutira

1

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

Daniel Röshammar

2

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

Emmanuel Chigutsa

3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

Prosper Chonzi

4

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

Michael Ashton

5

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

Charles Nhachi

6

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

publication date

5 December 2007

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

European Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

64

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

357-365

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

4

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

https://scigraph.springernature.com/pub.10.1007/s00228-007-0412-3

0 references

Sex is a major determinant of CYP3A4 expression in human liver

1 reference

https://api.crossref.org/works/10.1007%2FS00228-007-0412-3

21 January 2018

Population pharmacokinetics and effects of efavirenz in patients with human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1007%2FS00228-007-0412-3

21 January 2018

HIV/AIDS and TB.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liver toxicity induced by non-nucleoside reverse transcriptase inhibitors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tolerance and acceptability of an efavirenz-based regimen in 740 adults (predominantly women) in West Africa

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetics and pharmacodynamics of efavirenz, nelfinavir, and indinavir: Adult AIDS Clinical Trial Group Study 398.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PsN-Toolkit--a collection of computer intensive statistical methods for non-linear mixed effect modeling using NONMEM.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of sequential three-drug regimens as initial therapy for HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interpatient variability in the pharmacokinetics of the HIV non-nucleoside reverse transcriptase inhibitor efavirenz: the effect of gender, race, and CYP2B6 polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetics of efavirenz in an unselected cohort of HIV-1-infected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term results of initial therapy with abacavir and Lamivudine combined with Efavirenz, Amprenavir/Ritonavir, or Stavudine

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Population pharmacokinetic meta-analysis with efavirenz

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simulation of clinical trials

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcomes after two years of providing antiretroviral treatment in Khayelitsha, South Africa.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Target concentration intervention: beyond Y2K

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The functional role of CYP2B6 in human drug metabolism: substrates and inhibitors in vitro, in vivo and in silico.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiretroviral-associated toxicity among HIV-1-seropositive pregnant women in Mozambique receiving nevirapine-based regimens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatotoxicity during nevirapine-based fixed-dose combination antiretroviral therapy in kampala, Uganda

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Initial response to highly active antiretroviral therapy in HIV-1C-infected adults in a public sector treatment program in Botswana

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tuberculosis and HIV interaction in sub-Saharan Africa: impact on patients and programmes; implications for policies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe psychosis in an African woman due to the antiretroviral agent efavirenz

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Factors associated with efavirenz discontinuation in a large community-based sample of patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic CYP2B6 expression: gender and ethnic differences and relationship to CYP2B6 genotype and CAR (constitutive androstane receptor) expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic responses to AZT + 3TC + EFV in advanced antiretroviral naive HIV type 1-infected Ugandan patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex is a major determinant of CYP3A4 expression in human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/18057928

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00228-007-0412-3

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

1 reference

Europe PubMed Central

22 December 2017

http://europepmc.org/abstract/MED/18057928

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