(Q46529262)

22 December 2017

title

A novel polymorphic cytochrome P450 formed by splicing of CYP3A7 and the pseudogene CYP3AP1. (English)

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22 December 2017

Cristina Rodríguez-Antona

author

1

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22 December 2017

Magnus Ingelman-Sundberg

5

object named as

Magnus Ingelman-Sundberg

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Anders Rane

4

object named as

Anders Rane

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22 December 2017

author name string

Magnus Axelson

2

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22 December 2017

Charlotta Otter

3

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22 December 2017

language of work or name

English

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publication date

2 June 2005

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22 December 2017

Journal of Biological Chemistry

published in

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22 December 2017

volume

280

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22 December 2017

issue

31

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22 December 2017

page(s)

28324-28331

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22 December 2017

The human cytochrome P450 3A locus. Gene evolution by capture of downstream exons

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1 reference

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Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression

21 January 2018

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Cloning and tissue distribution of a novel human cytochrome p450 of the CYP3A subfamily, CYP3A43.

21 January 2018

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Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth

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Developmental expression of the major human hepatic CYP3A enzymes

21 January 2018

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Molecular mechanisms of polymorphic CYP3A7 expression in adult human liver and intestine

21 January 2018

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Differential catalytic properties in metabolism of endogenous and exogenous substrates among CYP3A enzymes expressed in COS-7 cells

21 January 2018

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Human cytochrome P450s involved in the metabolism of 9-cis- and 13-cis-retinoic acids

21 January 2018

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Cocaine metabolism in human fetal and adult liver microsomes is related to cytochrome P450 3A expression.

21 January 2018

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Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4

21 January 2018

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Identification and phenotype characterization of two CYP3A haplotypes causing different enzymatic capacity in fetal livers

21 January 2018

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ENZYME-STRUCTURE RELATIONSHIPS IN THE ENDOPLASMIC RETICULUM OF RAT LIVER : A Morphological and Biochemical Study

21 January 2018

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Comparative analysis of CYP3A expression in human liver suggests only a minor role for CYP3A5 in drug metabolism

21 January 2018

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Maximizing the expression of mammalian cytochrome P-450 monooxygenase activities in yeast cells

21 January 2018

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Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5.

21 January 2018

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Chimeras of the human cytochrome P450 1A family produced in yeast. Accumulation in microsomal membranes, enzyme kinetics and stability

21 January 2018

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Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides

21 January 2018

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Bile acid synthesis in cultured human hepatocytes: support for an alternative biosynthetic pathway to cholic acid

21 January 2018

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The lithocholic acid 6 beta-hydroxylase cytochrome P-450, CYP 3A10, is an active catalyst of steroid-hormone 6 beta-hydroxylation

21 January 2018

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An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

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Intergenic mRNA molecules resulting from trans-splicing

21 January 2018

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Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450.

21 January 2018

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CYP3A variation and the evolution of salt-sensitivity variants

21 January 2018

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Genotype???phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women

21 January 2018

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Defining relationships between the known members of the cytochrome P450 3A subfamily, including five putative chimpanzee members.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M502309200

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22 December 2017

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22 December 2017