(Q46607308)

23 December 2017

title

IKKbeta is essential for protecting T cells from TNFalpha-induced apoptosis (English)

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23 December 2017

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3

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23 December 2017

author name string

U Senftleben

series ordinal

1

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23 December 2017

Z W Li

series ordinal

2

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23 December 2017

M Karin

series ordinal

4

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23 December 2017

language of work or name

English

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publication date

1 March 2001

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23 December 2017

published in

Immunity

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23 December 2017

volume

14

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23 December 2017

page(s)

217-230

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23 December 2017

issue

3

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23 December 2017

High levels of c-rel expression are associated with programmed cell death in the developing avian embryo and in bone marrow cells in vitro

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-kappa B

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Constitutive NF-kappa B activation, enhanced granulopoiesis, and neonatal lethality in I kappa B alpha-deficient mice

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Pyrrolidine dithiocarbamate, a potent inhibitor of nuclear factor kappa B (NF-kappa B) activation, prevents apoptosis in human promyelocytic leukemia HL-60 cells and thymocytes

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Perturbation of the T lymphocyte lineage in transgenic mice expressing a constitutive repressor of nuclear factor (NF)-kappaB.

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Expression of relB is required for the development of thymic medulla and dendritic cells

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The development of B cells in the bone marrow is controlled by the balance between cell-autonomous mechanisms and signals from the microenvironment.

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NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses

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Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

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Requirement for NF-kappaB in osteoclast and B-cell development

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Genetic approaches in mice to understand Rel/NF-kappaB and IkappaB function: transgenics and knockouts

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression

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A 3' transcriptional enhancer regulates tissue-specific expression of the human CD2 gene.

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Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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7 January 2021

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

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7 January 2021

Female mice heterozygous for IKK gamma/NEMO deficiencies develop a dermatopathy similar to the human X-linked disorder incontinentia pigmenti

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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NEMO/IKK gamma-deficient mice model incontinentia pigmenti.

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7 January 2021

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

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7 January 2021

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

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7 January 2021

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

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7 January 2021

Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900104-2

7 January 2021

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

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7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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7 January 2021

p50-NF-kappaB complexes partially compensate for the absence of RelB: severely increased pathology in p50(-/-)relB(-/-) double-knockout mice

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7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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7 January 2021

10.1016/S1074-7613(01)00104-2

Identifiers

DOI

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23 December 2017

PubMed ID

11290332

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23 December 2017