(Q46699326)

24 December 2017

title

Modulation of T cell homeostasis and alloreactivity under continuous FTY720 exposure (English)

1 reference

24 December 2017

author name string

Barbara Metzler

1

1 reference

24 December 2017

Patrick Gfeller

2

1 reference

24 December 2017

Grazyna Wieczorek

3

1 reference

24 December 2017

Jianping Li

4

1 reference

24 December 2017

Barbara Nuesslein-Hildesheim

5

1 reference

24 December 2017

Andreas Katopodis

6

1 reference

24 December 2017

Matthias Mueller

7

1 reference

24 December 2017

Volker Brinkmann

8

1 reference

24 December 2017

publication date

14 March 2008

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24 December 2017

published in

International Immunology

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24 December 2017

volume

20

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24 December 2017

issue

5

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24 December 2017

page(s)

633-644

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24 December 2017

FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity

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1 reference

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FTY720, a novel immunomodulator: efficacy and safety results from the first phase 2A study in de novo renal transplantation

21 January 2018

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Oral fingolimod (FTY720) for relapsing multiple sclerosis

21 January 2018

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

21 January 2018

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Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

21 January 2018

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Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

21 January 2018

1 reference

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Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

21 January 2018

1 reference

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Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network

21 January 2018

1 reference

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Transient T cell accumulation in lymph nodes and sustained lymphopenia in mice treated with FTY720.

21 January 2018

1 reference

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Conversion of naive T cells to a memory-like phenotype in lymphopenic hosts is not related to a homeostatic mechanism that fills the peripheral naive T cell pool.

21 January 2018

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Different contributions of thymopoiesis and homeostasis-driven proliferation to the reconstitution of naive and memory T cell compartments

21 January 2018

1 reference

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FTY720 mediates apoptosis-independent lymphopenia in human renal allograft recipients: different effects on CD62L+ and CCR5+ T lymphocytes.

21 January 2018

1 reference

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Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

21 January 2018

1 reference

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Lymphopenia-induced homeostatic proliferation of CD8+ T cells is a mechanism for effective allogeneic skin graft rejection following burn injury.

21 January 2018

1 reference

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Strong and ubiquitous expression of transgenes targeted into the beta-actin locus by Cre/lox cassette replacement.

21 January 2018

1 reference

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Combinations of anti-LFA-1, everolimus, anti-CD40 ligand, and allogeneic bone marrow induce central transplantation tolerance through hemopoietic chimerism, including protection from chronic heart allograft rejection

21 January 2018

1 reference

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Turnover of naive- and memory-phenotype T cells

21 January 2018

1 reference

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Costimulation blockade, busulfan, and bone marrow promote titratable macrochimerism, induce transplantation tolerance, and correct genetic hemoglobinopathies with minimal myelosuppression.

21 January 2018

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Population biology of lymphocytes: the flight for survival

21 January 2018

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The life span of naive alpha/beta T cells in secondary lymphoid organs

21 January 2018

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Peripheral selection of T cell repertoires: the role of continuous thymus output

21 January 2018

1 reference

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IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

21 January 2018

1 reference

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Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Reduced expression of Bcl-2 in CD8+ T cells deficient in the IL-15 receptor alpha-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Continued maturation of thymic emigrants in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Naïve cytotoxic T lymphocytes spontaneously acquire effector function in lymphocytopenic recipients: A pitfall for T cell memory studies?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

The involvement of the intestinal microflora in the expansion of CD4+ T cells with a naive phenotype in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Homeostatic proliferation is a barrier to transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Initial T cell frequency dictates memory CD8+ T cell lineage commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Cutting edge: migration to nonlymphoid tissues results in functional conversion of central to effector memory CD8 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Anatomical heterogeneity of memory CD4+ T cells due to reversible adaptation to the microenvironment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

The generation of protective memory-like CD8+ T cells during homeostatic proliferation requires CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Cutting edge: CCR7+ and CCR7- memory T cells do not differ in immediate effector cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Heterologous immunity provides a potent barrier to transplantation tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

FTY720 alters lymphocyte homing and protects allografts without inducing general immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Bag-1 up-regulation in anti-CD4 mAb-treated allo-activated T cell confers resistance to activation-induced cell death (AICD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Identification of regulatory T cells in tolerated allografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN023

21 January 2018

Identifiers

DOI

10.1093/INTIMM/DXN023

1 reference

24 December 2017

1 reference

24 December 2017