(Q46765640)

English

An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets

scientific article published on 7 February 2008

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scholarly article

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

An unbiased evaluation of CK2 inhibitors by chemoproteomics: characterization of inhibitor effects on CK2 and identification of novel inhibitor targets (English)

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

1 reference

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Maria Bretner

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

author name string

James S Duncan

1

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

Laszlo Gyenis

2

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

John Lenehan

3

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

Lee M Graves

5

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

Timothy A Haystead

6

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

David W Litchfield

7

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

publication date

7 February 2008

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

Molecular & Cellular Proteomics

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

7

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Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

1077-1088

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

6

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

Current and emerging treatment options in chronic myeloid leukemia

1 reference

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The druggable genome

1 reference

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21 January 2018

Protein kinase CK2: a newcomer in the 'druggable kinome'.

1 reference

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21 January 2018

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

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Antisense oligonucleotides against protein kinase CK2-alpha inhibit growth of squamous cell carcinoma of the head and neck in vitro

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Protein kinase CK2 in mammary gland tumorigenesis

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CK2 phosphorylation of the armadillo repeat region of beta-catenin potentiates Wnt signaling

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Constitutive phosphorylation of I kappa B alpha by casein kinase II.

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Protein kinase CK2 phosphorylates and upregulates Akt/PKB.

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Too much of a good thing: the role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2.

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Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

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Protein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cells

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Phosphorylation of presenilin-2 regulates its cleavage by caspases and retards progression of apoptosis

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21 January 2018

Development and exploitation of CK2 inhibitors

1 reference

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21 January 2018

Optimization of protein kinase CK2 inhibitors derived from 4,5,6,7-tetrabromobenzimidazole

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21 January 2018

2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole: a novel powerful and selective inhibitor of protein kinase CK2.

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21 January 2018

Selectivity of 4,5,6,7-tetrabromobenzimidazole as an ATP-competitive potent inhibitor of protein kinase CK2 from various sources.

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21 January 2018

Gamma-phosphate-linked ATP-sepharose for the affinity purification of protein kinases. Rapid purification to homogeneity of skeletal muscle mitogen-activated protein kinase kinase

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21 January 2018

Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells

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21 January 2018

Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines.

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21 January 2018

Tetrabromobenzotriazole (TBBt) and tetrabromobenzimidazole (TBBz) as selective inhibitors of protein kinase CK2: evaluation of their effects on cells and different molecular forms of human CK2.

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Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis

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21 January 2018

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

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21 January 2018

Validation of protein kinase CK2 as oncological target.

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21 January 2018

Phosphorylation regulates the stability of the regulatory CK2beta subunit

1 reference

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21 January 2018

Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

1 reference

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21 January 2018

Discovery of novel targets of quinoline drugs in the human purine binding proteome

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21 January 2018

NRH:quinone reductase 2: an enzyme of surprises and mysteries

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21 January 2018

Deficiency of NRH:quinone oxidoreductase 2 differentially regulates TNF signaling in keratinocytes: up-regulation of apoptosis correlates with down-regulation of cell survival kinases.

1 reference

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21 January 2018

Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors

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21 January 2018

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

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21 January 2018

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

1 reference

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21 January 2018

Crystal structure of quinone reductase 2 in complex with resveratrol

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21 January 2018

Features and potentials of ATP-site directed CK2 inhibitors

1 reference

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21 January 2018

Crystal structure of quinone reductase 2 in complex with cancer prodrug CB1954

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21 January 2018

Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction

1 reference

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21 January 2018

Identifiers

10.1074/MCP.M700559-MCP200

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

1 reference

Europe PubMed Central

25 December 2017

http://europepmc.org/abstract/MED/18258654

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