(Q46793124)

25 December 2017

title

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76. (English)

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25 December 2017

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5

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25 December 2017

Michael L Dustin

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25 December 2017

Takashi Saito

8

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25 December 2017

Makio Tokunaga

object named as

Makio Tokunaga

6

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author name string

Tadashi Yokosuka

1

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25 December 2017

Kumiko Sakata-Sogawa

2

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25 December 2017

Wakana Kobayashi

3

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25 December 2017

Michio Hiroshima

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25 December 2017

language of work or name

English

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publication date

6 November 2005

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25 December 2017

published in

Nature Immunology

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25 December 2017

volume

6

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25 December 2017

issue

12

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25 December 2017

page(s)

1253-1262

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25 December 2017

Three-dimensional segregation of supramolecular activation clusters in T cells

cites work

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7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

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7 January 2021

T-cell-antigen recognition and the immunological synapse

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7 January 2021

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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7 January 2021

Role of the cytoskeleton during leukocyte responses

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7 January 2021

Staging and resetting T cell activation in SMACs

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7 January 2021

ERM-dependent movement of CD43 defines a novel protein complex distal to the immunological synapse

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7 January 2021

In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern.

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7 January 2021

Exclusion of CD43 from the immunological synapse is mediated by phosphorylation-regulated relocation of the cytoskeletal adaptor moesin

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7 January 2021

T cell receptor signaling precedes immunological synapse formation

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7 January 2021

Direct observation of ligand recognition by T cells.

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7 January 2021

Imaging antigen-induced PI3K activation in T cells

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7 January 2021

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

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7 January 2021

The immunological synapse balances T cell receptor signaling and degradation

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7 January 2021

T cell receptor (TCR) clustering in the immunological synapse integrates TCR and costimulatory signaling in selected T cells

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7 January 2021

T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

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7 January 2021

Continuous T cell receptor signaling required for synapse maintenance and full effector potential

1 reference

7 January 2021

Costimulation: building an immunological synapse

1 reference

7 January 2021

Dynamic imaging of T cell-dendritic cell interactions in lymph nodes

1 reference

7 January 2021

Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

1 reference

7 January 2021

Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation

1 reference

7 January 2021

Calcineurin imposes T cell unresponsiveness through targeted proteolysis of signaling proteins

1 reference

7 January 2021

The duration of antigenic stimulation determines the fate of naive and effector T cells.

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7 January 2021

Dynamic programming of CD8+ T lymphocyte responses

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7 January 2021

Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling

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7 January 2021

Immunological synapses are versatile structures enabling selective T cell polarization.

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7 January 2021

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

1 reference

7 January 2021

Dynamic molecular interactions linking the T cell antigen receptor to the actin cytoskeleton.

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7 January 2021

Dynamics of the immunological synapse: finding, establishing and solidifying a connection

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7 January 2021

Differential clustering of CD4 and CD3zeta during T cell recognition

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7 January 2021

Multifocal structure of the T cell - dendritic cell synapse

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7 January 2021

T cell activation stimulates the association of enzymatically active tyrosine-phosphorylated ZAP-70 with the Crk adapter proteins

1 reference

7 January 2021

Mechanism of recruitment of WASP to the immunological synapse and of its activation following TCR ligation

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7 January 2021

SLP-76 coordinates Nck-dependent Wiskott-Aldrich syndrome protein recruitment with Vav-1/Cdc42-dependent Wiskott-Aldrich syndrome protein activation at the T cell-APC contact site

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7 January 2021

Communication between the TCR and integrins: role of the molecular adapter ADAP/Fyb/Slap

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7 January 2021

Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton

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7 January 2021

Stop and go traffic to tune T cell responses

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7 January 2021

A role for the immunological synapse in lineage commitment of CD4 lymphocytes.

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7 January 2021

Serial triggering of many T-cell receptors by a few peptide-MHC complexes

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7 January 2021

The immunological synapse: required for T cell receptor signalling or directing T cell effector function?

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7 January 2021

Information transfer at the immunological synapse.

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7 January 2021

Erratum: Costimulation and endogenous MHC ligands contribute to T cell recognition

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7 January 2021

A monomeric red fluorescent protein

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7 January 2021

Cell-substrate contacts illuminated by total internal reflection fluorescence

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7 January 2021

Single molecule imaging of fluorophores and enzymatic reactions achieved by objective-type total internal reflection fluorescence microscopy

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7 January 2021

Identifiers

DOI

10.1038/NI1272

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25 December 2017

Dimensions Publication ID

1048674669

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25 December 2017