(Q46845177)

25 December 2017

title

Alemtuzumab induces caspase-independent cell death in human chronic lymphocytic leukemia cells through a lipid raft-dependent mechanism (English)

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25 December 2017

chronic lymphocytic leukemia

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A P Mone

1

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25 December 2017

C Cheney

2

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25 December 2017

A L Banks

3

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25 December 2017

S Tridandapani

4

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25 December 2017

N Mehter

5

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25 December 2017

S Guster

6

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25 December 2017

T Lin

7

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25 December 2017

C F Eisenbeis

8

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25 December 2017

D C Young

9

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25 December 2017

J C Byrd

10

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25 December 2017

publication date

1 February 2006

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25 December 2017

published in

Leukemia

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25 December 2017

volume

20

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25 December 2017

page(s)

272-279

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25 December 2017

issue

2

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25 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.leu.2404014

exact match

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Differential CD52 expression by distinct myeloid dendritic cell subsets: implications for alemtuzumab activity at the level of antigen presentation in allogeneic graft-host interactions in transplantation

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The glycosylphosphatidylinositol-anchored lymphocyte antigen CDw52 is associated with the epididymal maturation of human spermatozoa

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Levels of expression of CD52 in normal and leukemic B and T cells: correlation with in vivo therapeutic responses to Campath-1H

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Efficient complement-mediated lysis of cells containing the CAMPATH-1 (CDw52) antigen

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Cross-linking of the CAMPATH-1 antigen (CD52) triggers activation of normal human T lymphocytes

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Cross-linking of the CAMPATH-1 antigen (CD52) mediates growth inhibition in human B- and T-lymphoma cell lines, and subsequent emergence of CD52-deficient cells

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Alemtuzumab (CAMPATH 1H) does not kill chronic lymphocytic leukemia cells in serum free medium

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7 January 2021

Clustered CD20 induced apoptosis: src-family kinase, the proximal regulator of tyrosine phosphorylation, calcium influx, and caspase 3-dependent apoptosis

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7 January 2021

The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism

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The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction

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CD47 ligation induces caspase-independent cell death in chronic lymphocytic leukemia

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Fully human, HLA-DR-specific monoclonal antibodies efficiently induce programmed death of malignant lymphoid cells

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Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells

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Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

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KRN5500: a novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis

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7 January 2021

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7 January 2021

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7 January 2021

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Lipid rafts: elusive or illusive?

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Functional rafts in cell membranes

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7 January 2021

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7 January 2021

Altered membrane-associated functions in chronic lymphocytic leukemia cells

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7 January 2021

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7 January 2021

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7 January 2021

Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization

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7 January 2021

CD20-mediated apoptosis: signalling through lipid rafts

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2404014

1 reference

25 December 2017

PubMed ID

16341049

1 reference

25 December 2017