(Q46868425)

26 December 2017

title

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference. (English)

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26 December 2017

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7

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26 December 2017

author name string

Selda Samakoglu

1

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26 December 2017

Leszek Lisowski

2

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26 December 2017

Tulin Budak-Alpdogan

3

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26 December 2017

Yelena Usachenko

4

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26 December 2017

Santina Acuto

5

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26 December 2017

Rosalba Di Marzo

6

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26 December 2017

Ping Zhu

8

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26 December 2017

John F Tisdale

9

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26 December 2017

Isabelle Rivière

10

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26 December 2017

Michel Sadelain

11

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26 December 2017

publication date

25 December 2005

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26 December 2017

published in

Nature Biotechnology

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26 December 2017

volume

24

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26 December 2017

page(s)

89-94

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26 December 2017

issue

1

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26 December 2017

https://scigraph.springernature.com/pub.10.1038/nbt1176

exact match

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cites work

RNA interference in adult mice.

1 reference

Gene therapy progress and prospects: recent progress in transgene and RNAi expression cassettes

21 January 2018

1 reference

Pathophysiology of sickle cell disease: role of cellular and genetic modifiers

21 January 2018

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Activation of the interferon system by short-interfering RNAs

21 January 2018

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Determinants of interferon-stimulated gene induction by RNAi vectors

21 January 2018

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Analysis of double-stranded RNA-induced apoptosis pathways using interferon-response noninducible small interfering RNA expression vector library

21 January 2018

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Negative feedback inhibition of HIV-1 by TAT-inducible expression of siRNA.

21 January 2018

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Gene silencing in androgen-responsive prostate cancer cells from the tissue-specific prostate-specific antigen promoter

21 January 2018

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Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

21 January 2018

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Influence of RNA secondary structure on the pre-mRNA splicing process

21 January 2018

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Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy.

21 January 2018

1 reference

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

21 January 2018

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Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences

21 January 2018

1 reference

RNAse III-mediated degradation of unspliced pre-mRNAs and lariat introns

21 January 2018

1 reference

Pharmacologic manipulation of fetal hemoglobin in the hemoglobinopathies

21 January 2018

1 reference

Correction of sickle cell disease in transgenic mouse models by gene therapy

21 January 2018

1 reference

Genetic correction of sickle cell disease: insights using transgenic mouse models

21 January 2018

1 reference

Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursors

21 January 2018

1 reference

Activation of human gamma-globin gene expression via triplex-forming oligonucleotide (TFO)-directed mutations in the gamma-globin gene 5' flanking region

21 January 2018

1 reference

Exploring strategies for the design of artificial transcription factors: targeting sites proximal to known regulatory regions for the induction of gamma-globin expression and the treatment of sickle cell disease

21 January 2018

1 reference

Occurrence of leukaemia following gene therapy of X-linked SCID.

21 January 2018

1 reference

Differences of globin transgene expression in stably transfected cell lines and transgenic mice

21 January 2018

1 reference

Expression of a human beta-globin transgene in erythroid cells derived from retrovirally transduced transplantable human fetal liver and cord blood cells

21 January 2018

1 reference

Therapeutic applications of RNA interference: recent advances in siRNA design

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Ex vivo expansion of neutrophil precursor cells from fresh and cryopreserved cord blood cells

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NBT1176

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26 December 2017

PubMed ID

16378095

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26 December 2017