(Q46890878)

26 December 2017

title

Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells. (English)

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26 December 2017

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4

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26 December 2017

author name string

S Watanabe

1

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26 December 2017

H Umehara

2

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26 December 2017

K Murayama

3

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26 December 2017

T Kimura

5

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26 December 2017

T Nakano

6

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26 December 2017

language of work or name

English

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publication date

1 May 2006

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26 December 2017

published in

Oncogene

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26 December 2017

volume

25

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26 December 2017

page(s)

2697-2707

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26 December 2017

issue

19

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26 December 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1209307

exact match

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cites work

Rex-1, a gene encoding a transcription factor expressed in the early embryo, is regulated via Oct-3/4 and Oct-6 binding to an octamer site and a novel protein, Rox-1, binding to an adjacent site

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7 January 2021

Leukemia inhibitory factor-dependent transcriptional activation in embryonic stem cells

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7 January 2021

Advances in protein kinase B signalling: AKTion on multiple fronts

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7 January 2021

Signalling, cell cycle and pluripotency in embryonic stem cells

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7 January 2021

Suppression of SHP-2 and ERK signalling promotes self-renewal of mouse embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

The phosphoinositide 3-kinase pathway

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7 January 2021

Self-renewal of teratocarcinoma and embryonic stem cells.

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7 January 2021

Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

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7 January 2021

LIF/STAT3 signaling fails to maintain self-renewal of human embryonic stem cells

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7 January 2021

Electroporation of cynomolgus monkey embryonic stem cells

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7 January 2021

Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo.

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7 January 2021

Upstream and downstream of mTOR

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7 January 2021

Maintenance of pluripotency in human embryonic stem cells is STAT3 independent

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7 January 2021

Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells

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7 January 2021

Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

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7 January 2021

Contribution of the PI3K/Akt/PKB signal pathway to maintenance of self-renewal in human embryonic stem cells

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Mouse germ cell-less as an essential component for nuclear integrity.

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7 January 2021

Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production

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7 January 2021

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

1 reference

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7 January 2021

Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells

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7 January 2021

WNT and beta-catenin signalling: diseases and therapies

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7 January 2021

Efficient gene transfer of a simian immuno-deficiency viral vector into cardiomyocytes derived from primate embryonic stem cells

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7 January 2021

In vitro development of primitive and definitive erythrocytes from different precursors

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Efficient selection for high-expression transfectants with a novel eukaryotic vector

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Regulation of embryonic stem cell self-renewal by phosphoinositide 3-kinase-dependent signaling.

1 reference

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7 January 2021

Oct-4: gatekeeper in the beginnings of mammalian development.

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7 January 2021

BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

A molecular programme for the specification of germ cell fate in mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

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7 January 2021

Essential role of AKT-1/protein kinase B alpha in PTEN-controlled tumorigenesis

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7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

1 reference

7 January 2021

Growth and differentiation of cynomolgus monkey ES cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

STAT3 is dispensable for maintenance of self-renewal in nonhuman primate embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Role of ERas in promoting tumour-like properties in mouse embryonic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1209307

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209307

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26 December 2017

PubMed ID

16407845

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26 December 2017