(Q46922846)

English

Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study.

scientific article published on 31 October 2007

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scholarly article

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Effect of human renal cationic transporter inhibition on the pharmacokinetics of varenicline, a new therapy for smoking cessation: an in vitro-in vivo study. (English)

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

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author name string

Feng B

1

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Obach RS

2

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Burstein AH

3

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Clark DJ

4

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

de Morais SM

5

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Faessel HM

6

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

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publication date

31 October 2007

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Clinical Pharmacology & Therapeutics

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Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

83

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Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

567-576

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Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

4

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

Reduction of metformin renal tubular secretion by cimetidine in man

1 reference

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Effect of cimetidine on renal function in man.

1 reference

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21 January 2018

Mechanisms and clinical implications of renal drug excretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

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Cellular and molecular aspects of drug transport in the kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

The molecular biology of renal organic anion and organic cation transporters.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

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Mechanisms mediating renal secretion of organic anions and cations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

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Transporters involved in the elimination of drugs in the kidney: organic anion transporters and organic cation transporters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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Structure of renal organic anion and cation transporters

1 reference

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7 January 2021

based on heuristic

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Varenicline: an alpha4beta2 nicotinic receptor partial agonist for smoking cessation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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Pharmacological profile of the alpha4beta2 nicotinic acetylcholine receptor partial agonist varenicline, an effective smoking cessation aid

1 reference

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7 January 2021

based on heuristic

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Nicotine activation of alpha4* receptors: sufficient for reward, tolerance, and sensitization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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A double-blind study evaluating the long-term safety of varenicline for smoking cessation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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Metabolism and disposition of varenicline, a selective alpha4beta2 acetylcholine receptor partial agonist, in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

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inferred from DOI database lookup

Impact of drug transporter studies on drug discovery and development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple-dose pharmacokinetics of the selective nicotinic receptor partial agonist, varenicline, in healthy smokers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

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Cimetidine-procainamide pharmacokinetic interaction in man: Evidence of competition for tubular secretion of basic drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Renal transport of drugs: specificity and molecular mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

The clinical pharmacokinetics of levofloxacin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of cimetidine and ranitidine on pharmacokinetics and pharmacodynamics of a single dose of dofetilide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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Pharmacokinetics of cimetidine after single doses and during continuous treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Accurate measurement of impaired glomerular filtration using single-dose oral cimetidine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of cimetidine on renal function in normal man

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Evaluation of P-glycoprotein-mediated renal drug interactions in an MDR1-MDCK model

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Human breast cancer resistance protein: interactions with steroid drugs, hormones, the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine, and transport of cimetidine.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

A human transporter protein that mediates the final excretion step for toxic organic cations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification and functional characterization of a new human kidney-specific H+/organic cation antiporter, kidney-specific multidrug and toxin extrusion 2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

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Concomitant use of mirtazapine and cimetidine: a drug-drug interaction study in healthy male subjects

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

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Different transport properties between famotidine and cimetidine by human renal organic ion transporters (SLC22A).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

based on heuristic

inferred from DOI database lookup

Metformin transport by renal basolateral organic cation transporter hOCT2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CLPT.6100405

7 January 2021

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inferred from DOI database lookup

Metformin is a superior substrate for renal organic cation transporter OCT2 rather than hepatic OCT1.

1 reference

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based on heuristic

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Characterization of uremic toxin transport by organic anion transporters in the kidney

1 reference

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Prediction of creatinine clearance from serum creatinine

1 reference

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based on heuristic

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Single-dose pharmacokinetics of varenicline, a selective nicotinic receptor partial agonist, in healthy smokers and nonsmokers

1 reference

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Drug interactions at the renal level. Implications for drug development

1 reference

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Identifiers

10.1038/SJ.CLPT.6100405

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

1 reference

Europe PubMed Central

26 December 2017

http://europepmc.org/abstract/MED/17971819

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