(Q47208435)

English

An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity.

scientific article published on 28 December 2017

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scholarly article

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

An engineered cell line lacking OGG1 and MUTYH glycosylases implicates the accumulation of genomic 8-oxoguanine as the basis for paraquat mutagenicity. (English)

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

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object named as

Bogdan I Fedeles

2

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author name string

Preechaya Tajai

1

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

Tawit Suriyo

3

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

Panida Navasumrit

4

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

Jantamas Kanitwithayanun

5

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

John M Essigmann

6

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

Jutamaad Satayavivad

7

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

publication date

28 December 2017

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

Free Radical Biology and Medicine

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

116

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Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

64-72

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

describes a project that uses

0 references

CHO-AS52 Ogg1(-/-)-Mutyh(-/-)

0 references

Mutational spectra of aflatoxin B1 in vivo establish biomarkers of exposure for human hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Effects of Antioxidant N-acetylcysteine Against Paraquat-Induced Oxidative Stress in Vital Tissues of Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

The γH2AX DNA damage assay from a drop of blood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Paraquat Induces Apoptosis through a Mitochondria-Dependent Pathway in RAW264.7 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

BRCA1 and BRCA2 protect against oxidative DNA damage converted into double-strand breaks during DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Cellular levels of 8-oxoguanine in either DNA or the nucleotide pool play pivotal roles in carcinogenesis and survival of cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Targeting DNA repair pathways for cancer treatment: what's new?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

8-oxoguanine causes spontaneous de novo germline mutations in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Paraquat-induced reactive oxygen species inhibit neutrophil apoptosis via a p38 MAPK/NF-κB-IL-6/TNF-α positive-feedback circuit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

New insights into antioxidant strategies against paraquat toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Genome engineering using the CRISPR-Cas9 system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Oxidative stress-induced mutagenesis in single-strand DNA occurs primarily at cytosines and is DNA polymerase zeta-dependent only for adenines and guanines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Oxidative DNA damage and inflammatory responses in cultured human cells and in humans exposed to traffic-related particles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

AFB(1) -induced mutagenesis of the gpt gene in AS52 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Antioxidant effect of silymarin on paraquat-induced human lung adenocarcinoma A549 cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Oxidatively induced DNA damage: mechanisms, repair and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Endogenously induced DNA double strand breaks arise in heterochromatic DNA regions and require ataxia telangiectasia mutated and Artemis for their repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Oxidative stress, inflammation, and cancer: how are they linked?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

gammaH2AX: a sensitive molecular marker of DNA damage and repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Oxidative stress and oxidative damage in carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Cytotoxic and genotoxic effects of paraquat in Hordeum vulgare and human lymphocytes in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Base-excision repair of oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Nuclear and mitochondrial DNA repair: similar pathways?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Mutagenicity of reactive oxygen and nitrogen species as detected by co-culture of activated inflammatory leukocytes and AS52 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Paraquat in developing countries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Evaluation of the genotoxic properties of paraquat in V79 Chinese hamster cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

The genotoxicity of the waste water discharged from paraquat manufacturing and its pyridyl components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Detection of deletion mutations in pSV2gpt-transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Molecular analysis of spontaneous mutations at the gpt locus in Chinese hamster ovary (AS52) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

16 June 2018

Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Oxidative DNA damage in human cells induced by paraquat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Accelerating genome editing in CHO cells using CRISPR Cas9 and CRISPy, a web-based target finding tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

DNA damage-induced reactive oxygen species (ROS) stress response in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Evaluation of DNA damage in Chinese toad (Bufo bufo gargarizans) after in vivo exposure to sublethal concentrations of four herbicides using the comet assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Complex I is the major site of mitochondrial superoxide production by paraquat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Functional cooperation of Ogg1 and Mutyh in preventing G: C-->T: a transversions in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Induction of microsatellite mutations by oxidative agents in human lung cancer cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Determination of 8-hydroxy-deoxyguanosine formation in rat organs: assessment of paraquat-evoked oxidative DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

The effects of hydrogen peroxide on DNA repair activities.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5902796

14 August 2018

Photodamage and skin cancer among paraquat workers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29289706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The action of the herbicide paraquat on somatic and germ cells of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29289706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genotoxic evaluation of the herbicide paraquat in cultured human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29289706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29289706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

No significant paraquat-induced oxidative DNA damage in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29289706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dermal exposure to the herbicide-paraquat results in genotoxic and cytotoxic damage to germ cells in the male rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/29289706

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.FREERADBIOMED.2017.12.035

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

1 reference

Europe PubMed Central

16 June 2018

http://europepmc.org/abstract/PMC/5902796

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