(Q47388000)

15 January 2018

title

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. (English)

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15 January 2018

author

Alejandro Villarino

1

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15 January 2018

author name string

Linda Hibbert

2

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15 January 2018

Linda Lieberman

3

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15 January 2018

Emma Wilson

4

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15 January 2018

Tak Mak

5

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15 January 2018

Hiroki Yoshida

6

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15 January 2018

Robert A Kastelein

7

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15 January 2018

Christiaan Saris

8

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15 January 2018

Christopher A Hunter

9

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15 January 2018

language of work or name

English

0 references

publication date

1 November 2003

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15 January 2018

published in

Immunity

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15 January 2018

volume

19

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15 January 2018

page(s)

645-655

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15 January 2018

issue

5

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15 January 2018

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

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Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis

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Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

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Induction of cytotoxic T lymphocyte antigen 4 (CTLA-4) restricts clonal expansion of helper T cells

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WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production

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7 January 2021

IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

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7 January 2021

Transcription: tantalizing times for T cells

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STAT1 affects lymphocyte survival and proliferation partially independent of its role downstream of IFN-gamma

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Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii

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7 January 2021

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

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7 January 2021

SOCS-1 participates in negative regulation of LPS responses

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7 January 2021

Role of interleukin-10 in regulation of T-cell-dependent and T-cell-independent mechanisms of resistance to Toxoplasma gondii

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7 January 2021

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

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7 January 2021

Disruption of T helper 2-immune responses in Epstein-Barr virus-induced gene 3-deficient mice

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7 January 2021

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7 January 2021

IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells

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7 January 2021

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7 January 2021

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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7 January 2021

Interleukin-12: a cytokine at the interface of inflammation and immunity

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7 January 2021

Interleukin-12 and the regulation of innate resistance and adaptive immunity

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7 January 2021

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

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7 January 2021

Specific ablation of Stat3beta distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock

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7 January 2021

WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection

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7 January 2021

10.1016/S1074-7613(03)00300-5

Identifiers

DOI

1 reference

15 January 2018

PubMed ID

14614852

1 reference

15 January 2018