(Q47446256)

16 January 2018

title

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo. (English)

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16 January 2018

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Michael J May

5

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Kazuhiro Aoki

object named as

Kazuhiro Aoki

2

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author name string

Eijiro Jimi

1

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16 January 2018

Hiroaki Saito

3

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16 January 2018

Fulvio D'Acquisto

4

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16 January 2018

Ichiro Nakamura

6

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16 January 2018

Testuo Sudo

7

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16 January 2018

Takefumi Kojima

8

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16 January 2018

Fujio Okamoto

9

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16 January 2018

Hidefumi Fukushima

10

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16 January 2018

Koji Okabe

11

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16 January 2018

Keiichi Ohya

12

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16 January 2018

Sankar Ghosh

13

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16 January 2018

language of work or name

English

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publication date

23 May 2004

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16 January 2018

published in

Nature Medicine

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16 January 2018

volume

10

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page(s)

617-624

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issue

6

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16 January 2018

https://scigraph.springernature.com/pub.10.1038/nm1054

exact match

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cites work

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The diagnosis of osteoporosis

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The role of TNF alpha and IL-1 in rheumatoid arthritis

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Identification of osteoclasts and their mononuclear precursors. A comparative histological and histochemical study in hamster periodontitis.

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Mechanisms of cellular recruitment in aseptic loosening of prosthetic joint implants

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NF-kappa B in rheumatoid arthritis: a pivotal regulator of inflammation, hyperplasia, and tissue destruction

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RANKL and RANK as novel therapeutic targets for arthritis

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7 January 2021

Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis

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7 January 2021

Osteoclast differentiation and activation

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7 January 2021

Osteoclasts are essential for TNF-alpha-mediated joint destruction

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7 January 2021

A novel inhibitor of the tyrosine kinase Src suppresses phosphorylation of its major cellular substrates and reduces bone resorption in vitro and in rodent models in vivo

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7 January 2021

Herbimycin A, a pp60c-src tyrosine kinase inhibitor, inhibits osteoclastic bone resorption in vitro and hypercalcemia in vivo

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7 January 2021

Suppression of arthritic bone destruction by adenovirus-mediated csk gene transfer to synoviocytes and osteoclasts

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7 January 2021

Is NF-kappaB a useful therapeutic target in rheumatoid arthritis?

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7 January 2021

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

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7 January 2021

Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL

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7 January 2021

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

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7 January 2021

RANK is essential for osteoclast and lymph node development

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7 January 2021

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

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7 January 2021

Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2.

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7 January 2021

Requirement for NF-kappaB in osteoclast and B-cell development

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7 January 2021

Missing pieces in the NF-kappaB puzzle

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7 January 2021

The NF-kappa B activation pathway: a paradigm in information transfer from membrane to nucleus

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7 January 2021

The I kappa B kinase (IKK) and NF-kappa B: key elements of proinflammatory signalling

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7 January 2021

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

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7 January 2021

Characterization of the Ikappa B-kinase NEMO binding domain

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7 January 2021

Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide.

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7 January 2021

Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.

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7 January 2021

NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development

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7 January 2021

Transcription factors in bone: developmental and pathological aspects

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7 January 2021

RANK-L and RANK: T cells, bone loss, and mammalian evolution

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Bacterially induced bone destruction: mechanisms and misconceptions.

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7 January 2021

Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor kappaB (RANK) receptors

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7 January 2021

Collagen-induced arthritis, an animal model of autoimmunity

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7 January 2021

Vasoactive intestinal peptide prevents experimental arthritis by downregulating both autoimmune and inflammatory components of the disease

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7 January 2021

Relationship between Th1/Th2 cytokine patterns and the arthritogenic response in collagen-induced arthritis

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7 January 2021

The genetic and immunopathological processes underlying collagen-induced arthritis

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7 January 2021

Pyrrolidine dithiocarbamate attenuates the development of acute and chronic inflammation

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7 January 2021

In vivo imaging of NF-kappa B activity

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7 January 2021

The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

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7 January 2021

Identifiers

DOI

10.1038/NM1054

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16 January 2018

PubMed ID

15156202

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16 January 2018