(Q47594502)

http://europepmc.org/abstract/PMC/5676900

7 July 2018

title

Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor (English)

1 reference

http://europepmc.org/abstract/PMC/5676900

7 July 2018

author

Philippe Rochaix

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Nizar Serhan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Thomas Filleron

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Vincent Cavailles

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Michel Record

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Marc Poirot

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Sandrine Silvente-Poirot

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

author name string

Maud Voisin

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Philippe de Medina

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Arnaud Mallinger

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Florence Dalenc

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Emilie Huc-Claustre

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Julie Leignadier

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Régis Soules

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Grégory Ségala

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Aurélie Mougel

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Emmanuel Noguer

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Loubna Mhamdi

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Elodie Bacquié

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Luigi Iuliano

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Chiara Zerbinati

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Magali Lacroix-Triki

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Léonor Chaltiel

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Talal Al Saati

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Raphaelle Duprez-Paumier

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Camille Franchet

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Laetitia Ligat

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

Fréderic Lopez

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

language of work or name

English

0 references

publication date

12 October 2017

1 reference

http://europepmc.org/abstract/PMC/5676900

7 July 2018

published in

Proceedings of the National Academy of Sciences of the United States of America

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

volume

114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

issue

44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

page(s)

E9346-E9355

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

6 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5676900/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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10 July 2018

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10 July 2018

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Biased signalling from the glucocorticoid receptor: Renewed opportunity for tailoring glucocorticoid activity.

10 July 2018

1 reference

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Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Cholesterol metabolites exported from human brain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Estrogen receptors in breast carcinogenesis and endocrine therapy

10 July 2018

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An analysis of glucocorticoid receptor-mediated gene expression in BEAS-2B human airway epithelial cells identifies distinct, ligand-directed, transcription profiles with implications for asthma therapeutics

10 July 2018

1 reference

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Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation.

10 July 2018

1 reference

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Steroid signaling: ligand-binding promiscuity, molecular symmetry, and the need for gating.

10 July 2018

1 reference

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27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Glucocorticoid receptor antagonism as a novel therapy for triple-negative breast cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

11β-hydroxysteroid dehydrogenases: intracellular gate-keepers of tissue glucocorticoid action

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

BreastMark: an integrated approach to mining publicly available transcriptomic datasets relating to breast cancer outcome

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Interaction of glucocorticoid receptor (GR) with estrogen receptor (ER) α and activator protein 1 (AP1) in dexamethasone-mediated interference of ERα activity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

5,6-Epoxy-cholesterols contribute to the anticancer pharmacology of tamoxifen in breast cancer cells

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

bc-GenExMiner 3.0: new mining module computes breast cancer gene expression correlation analyses

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

How glucocorticoid receptors modulate the activity of other transcription factors: a scope beyond tethering.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Cholesterol-5,6-epoxides: chemistry, biochemistry, metabolic fate and cancer.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Activation of the glucocorticoid receptor is associated with poor prognosis in estrogen receptor-negative breast cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Glucocorticoid receptor and breast cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

A refined molecular taxonomy of breast cancer

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Expression profiling of nuclear receptors in the NCI60 cancer cell panel reveals receptor-drug and receptor-gene interactions

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Synthesis of new alkylaminooxysterols with potent cell differentiating activities: identification of leads for the treatment of cancer and neurodegenerative diseases.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Microsomal antiestrogen-binding site ligands induce growth control and differentiation of human breast cancer cells through the modulation of cholesterol metabolism.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Identification of polymorphisms in the human 11beta-hydroxysteroid dehydrogenase type 2 gene promoter: functional characterization and relevance for salt sensitivity.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Clinical and mechanistic aspects of glucocorticoid-induced chemotherapy resistance in the majority of solid tumors

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor farsenoid X receptor but not liver X receptor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Bile acids: natural ligands for an orphan nuclear receptor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Catalytic properties and inhibition of hepatic cholesterol-epoxide hydrolase

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Glucocorticoid Receptor:MegaTrans Switching Mediates the Repression of an ERα-Regulated Transcriptional Program.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

One step synthesis of 6-oxo-cholestan-3β,5α-diol.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Ozone exposure in vivo and formation of biologically active oxysterols in the lung

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5676900

Cholesterol metabolism and cancer: the good, the bad and the ugly

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29078321

12 December 2020

inferred from PubMed ID database lookup

Synthesis, binding and structure-affinity studies of new ligands for the microsomal anti-estrogen binding site (AEBS)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29078321

12 December 2020

inferred from PubMed ID database lookup

Cancer. Cholesterol and cancer, in the balance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29078321

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1707965114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29078321%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

29078321

1 reference