(Q47616484)

4 February 2018

title

Loss of RhoA promotes skin tumor formation and invasion by upregulation of RhoB. (English)

1 reference

4 February 2018

C Brakebusch

8

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author name string

A García-Mariscal

1

1 reference

4 February 2018

H Li

2

1 reference

4 February 2018

E Pedersen

3

1 reference

4 February 2018

K Peyrollier

4

1 reference

4 February 2018

K M Ryan

5

1 reference

4 February 2018

A Stanley

6

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4 February 2018

F Quondamatteo

7

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4 February 2018

language of work or name

English

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publication date

23 October 2017

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4 February 2018

published in

Oncogene

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4 February 2018

cites work

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1 reference

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Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility

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Rho-associated kinases in tumorigenesis: re-considering ROCK inhibition for cancer therapy

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RHOA inactivation enhances Wnt signalling and promotes colorectal cancer.

21 January 2018

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Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

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A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma

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Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.

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Activating mutations in genes related to TCR signaling in angioimmunoblastic and other follicular helper T-cell-derived lymphomas.

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Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

21 January 2018

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Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma

21 January 2018

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Discovery and saturation analysis of cancer genes across 21 tumour types

21 January 2018

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RhoB regulates cell migration through altered focal adhesion dynamics

21 January 2018

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RhoB regulates uPAR signalling

21 January 2018

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RhoB is dispensable for mouse development, but it modifies susceptibility to tumor formation as well as cell adhesion and growth factor signaling in transformed cells

21 January 2018

1 reference

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RhoA and RhoC have distinct roles in migration and invasion by acting through different targets

21 January 2018

1 reference

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RhoA is dispensable for skin development, but crucial for contraction and directed migration of keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma

21 January 2018

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Tumor-initiating stem cells of squamous cell carcinomas and their control by TGF-β and integrin/focal adhesion kinase (FAK) signaling

21 January 2018

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Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesis

21 January 2018

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RhoA and ROCK promote migration by limiting membrane protrusions

21 January 2018

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Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts.

21 January 2018

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RhoA determines disease progression by controlling neutrophil motility and restricting hyperresponsiveness

21 January 2018

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RhoB controls endothelial cell morphogenesis in part via negative regulation of RhoA.

21 January 2018

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RhoB promotes cancer initiation by protecting keratinocytes from UVB-induced apoptosis but limits tumor aggressiveness.

21 January 2018

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The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway

21 January 2018

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LC3/GABARAP family proteins: autophagy-(un)related functions

21 January 2018

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Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification

21 January 2018

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Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1

21 January 2018

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Geranylgeranylated, but not farnesylated, RhoB suppresses Ras transformation of NIH-3T3 cells

21 January 2018

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Differential localization of Rho GTPases in live cells: regulation by hypervariable regions and RhoGDI binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha

21 January 2018

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Actomyosin stress fiber mechanosensing in 2D and 3D

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

The effect of Rho kinase inhibition on long-term keratinocyte proliferation is rapid and conditional

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Simultaneous irradiation of fibroblasts and carcinoma cells repress the secretion of soluble factors able to stimulate carcinoma cell migration

21 January 2018

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Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Rac1 is crucial for Ras-dependent skin tumor formation by controlling Pak1-Mek-Erk hyperactivation and hyperproliferation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Structural Determinants Allowing Endolysosomal Sorting and Degradation of Endosomal GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

GTPase switch: Ras then Rho and Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

The RhoB small GTPase in physiology and disease

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2017.333

Cutaneous two-stage chemical carcinogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Rho GTPase knockout induction in primary keratinocytes from adult mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2017.333

Rho GTPase function in tumorigenesis

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29059167

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2017.333

1 reference

4 February 2018

1 reference

4 February 2018