(Q47670151)

4 February 2018

title

Downregulation of Bcl-2, FLIP or IAPs (XIAP and survivin) by siRNAs sensitizes resistant melanoma cells to Apo2L/TRAIL-induced apoptosis. (English)

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4 February 2018

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Chawla-Sarkar M

1

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4 February 2018

Bae SI

2

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4 February 2018

Reu FJ

3

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4 February 2018

Jacobs BS

4

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4 February 2018

Lindner DJ

5

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4 February 2018

Borden EC

6

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4 February 2018

publication date

1 August 2004

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4 February 2018

Cell Death & Differentiation

published in

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4 February 2018

volume

11

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4 February 2018

page(s)

915-923

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4 February 2018

issue

8

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4 February 2018

https://scigraph.springernature.com/pub.10.1038/sj.cdd.4401416

exact match

0 references

cites work

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The inhibitors of apoptosis (IAPs) and their emerging role in cancer

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Mitochondria and apoptosis

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BCL-2 family members and the mitochondria in apoptosis

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Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

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I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

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Inhibition of death receptor signals by cellular FLIP

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Validating survivin as a cancer therapeutic target

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IAP family proteins--suppressors of apoptosis

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IAP proteins: blocking the road to death's door

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Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

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Identification and characterization of a new member of the TNF family that induces apoptosis

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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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7 January 2021

IFN-beta pretreatment sensitizes human melanoma cells to TRAIL/Apo2 ligand-induced apoptosis

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7 January 2021

Gene silencing in mammals by small interfering RNAs

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Genomewide view of gene silencing by small interfering RNAs

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Short interfering RNA confers intracellular antiviral immunity in human cells

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7 January 2021

Expression profiling reveals off-target gene regulation by RNAi

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7 January 2021

Induction of an interferon response by RNAi vectors in mammalian cells

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7 January 2021

Activation of the interferon system by short-interfering RNAs

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7 January 2021

Suppression of NF-kappa B survival signaling by nitrosylcobalamin sensitizes neoplasms to the anti-tumor effects of Apo2L/TRAIL.

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X-linked IAP is a direct inhibitor of cell-death proteases

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Nuclease-resistant synthetic ribozymes: developing a new class of therapeutics

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PKR; a sentinel kinase for cellular stress

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7 January 2021

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

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7 January 2021

Actinomycin D and gemcitabine synergistically sensitize androgen-independent prostate cancer cells to Apo2L/TRAIL-mediated apoptosis

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7 January 2021

Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil

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7 January 2021

Clinical significance of the t(14;18) and BCL2 overexpression in follicular large cell lymphoma

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7 January 2021

Antisense therapy for cancer--the time of truth

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7 January 2021

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

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7 January 2021

Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.

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7 January 2021

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

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7 January 2021

Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

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7 January 2021

A decision between life and death during TNF-alpha-induced signaling

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7 January 2021

xIAP induces cell-cycle arrest and activates nuclear factor-kappaB : new survival pathways disabled by caspase-mediated cleavage during apoptosis of human endothelial cells

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https://api.crossref.org/works/10.1038%2FSJ.CDD.4401416

7 January 2021

Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401416

7 January 2021

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401416

7 January 2021

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4401416

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4401416

1 reference

4 February 2018

release_p77d4ofzcrgwfoptwbbnzbd7ty

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/p77d4ofzcrgwfoptwbbnzbd7ty

24 November 2022

mapped directly with Wikidata item

PubMed ID

15118763

1 reference

4 February 2018