(Q47847570)

6 February 2018

title

Fission yeast COP9/signalosome suppresses cullin activity through recruitment of the deubiquitylating enzyme Ubp12p. (English)

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6 February 2018

author

Wolfgang Dubiel

5

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6 February 2018

Dieter A Wolf

6

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6 February 2018

author name string

Chunshui Zhou

1

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6 February 2018

Susan Wee

2

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6 February 2018

Edward Rhee

3

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6 February 2018

Michael Naumann

4

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6 February 2018

publication date

1 April 2003

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6 February 2018

published in

Molecular Cell

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6 February 2018

volume

11

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6 February 2018

page(s)

927-938

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6 February 2018

issue

4

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6 February 2018

COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system

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7 January 2021

The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1

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Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway

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7 January 2021

Covalent modification of all members of human cullin family proteins by NEDD8

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7 January 2021

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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7 January 2021

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

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7 January 2021

A molecular basis for stabilization of the von Hippel-Lindau (VHL) tumor suppressor protein by components of the VHL ubiquitin ligase

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7 January 2021

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

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7 January 2021

Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

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7 January 2021

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

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7 January 2021

Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

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7 January 2021

Two F-box/WD-repeat proteins Pop1 and Pop2 form hetero- and homo-complexes together with cullin-1 in the fission yeast SCF (Skp1-Cullin-1-F-box) ubiquitin ligase.

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7 January 2021

Cytoskeletal regulation by the Nedd8 ubiquitin-like protein modification pathway

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7 January 2021

Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex

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7 January 2021

Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization

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7 January 2021

A novel protein modification pathway related to the ubiquitin system

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7 January 2021

Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome

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7 January 2021

Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1).

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7 January 2021

Deletion mutants in COP9/signalosome subunits in fission yeast Schizosaccharomyces pombe display distinct phenotypes

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7 January 2021

An intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells

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7 January 2021

Association with cullin partners protects ROC proteins from proteasome-dependent degradation

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7 January 2021

Covalent modifier NEDD8 is essential for SCF ubiquitin-ligase in fission yeast

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7 January 2021

The role of COP1 in repression of Arabidopsis photomorphogenic development

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7 January 2021

Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted developmental processes in Arabidopsis.

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7 January 2021

A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha

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7 January 2021

Feedback-regulated degradation of the transcriptional activator Met4 is triggered by the SCF(Met30 )complex

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7 January 2021

Interactions of the COP9 Signalosome with the E3 Ubiquitin Ligase SCFTIR1 in Mediating Auxin Response

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7 January 2021

A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits

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7 January 2021

The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice

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7 January 2021

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

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7 January 2021

Conservation of the COP9/signalosome in budding yeast

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7 January 2021

Regulation of ubiquitin-dependent processes by deubiquitinating enzymes

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https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

Ubiquitination and deubiquitination: targeting of proteins for degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

The F-box protein Skp2 is a ubiquitylation target of a Cul1-based core ubiquitin ligase complex: evidence for a role of Cul1 in the suppression of Skp2 expression in quiescent fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

F-box/WD-repeat proteins pop1p and Sud1p/Pop2p form complexes that bind and direct the proteolysis of cdc18p

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p

1 reference

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900136-9

7 January 2021

10.1016/S1097-2765(03)00136-9

Identifiers

DOI

1 reference

6 February 2018

PubMed ID

12718879

1 reference

6 February 2018