(Q48107132)

1 July 2018

title

Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice (English)

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1 July 2018

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8

C Ronald Kahn

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1 July 2018

Masahiro Konishi

1

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1 July 2018

Masaji Sakaguchi

2

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1 July 2018

Samuel M Lockhart

3

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1 July 2018

Weikang Cai

4

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1 July 2018

Mengyao Ella Li

5

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1 July 2018

Erica P Homan

6

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1 July 2018

Christian Rask-Madsen

7

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1 July 2018

language of work or name

English

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publication date

18 September 2017

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1 July 2018

Proceedings of the National Academy of Sciences of the United States of America

published in

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1 July 2018

volume

114

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1 July 2018

issue

40

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1 July 2018

page(s)

E8478-E8487

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1 July 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5635907/fullTextXML

inferred from PubMed Central ID database lookup

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Interactions between Gut Microbiota, Host Genetics and Diet Modulate the Predisposition to Obesity and Metabolic Syndrome

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Insulin resistance in brain alters dopamine turnover and causes behavioral disorders.

3 July 2018

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3 July 2018

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3 July 2018

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3 July 2018

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Insulin-induced endothelial cell cortical actin filament remodeling: a requirement for trans-endothelial insulin transport

3 July 2018

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Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance

3 July 2018

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Loss of insulin signaling in vascular endothelial cells accelerates atherosclerosis in apolipoprotein E null mice

3 July 2018

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3 July 2018

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The vascular actions of insulin control its delivery to muscle and regulate the rate-limiting step in skeletal muscle insulin action

3 July 2018

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Insulin signaling stimulates insulin transport by bovine aortic endothelial cells

3 July 2018

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3 July 2018

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3 July 2018

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The vascular endothelial cell mediates insulin transport into skeletal muscle

3 July 2018

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Reciprocal interactions of insulin and insulin-like growth factor I in receptor-mediated transport across the blood-brain barrier

3 July 2018

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Insulin at physiological concentrations selectively activates insulin but not insulin-like growth factor I (IGF-I) or insulin/IGF-I hybrid receptors in endothelial cells

3 July 2018

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3 July 2018

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Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization

3 July 2018

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3 July 2018

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3 July 2018

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3 July 2018

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PTP1B regulates leptin signal transduction in vivo

3 July 2018

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Role of brain insulin receptor in control of body weight and reproduction

3 July 2018

1 reference

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Insulin degradation: progress and potential

3 July 2018

1 reference

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Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin

3 July 2018

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Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells

3 July 2018

1 reference

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Transendothelial insulin transport is not saturable in vivo. No evidence for a receptor-mediated process

3 July 2018

1 reference

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Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain

3 July 2018

1 reference

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Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

3 July 2018

1 reference

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Nitric oxide release accounts for insulin's vascular effects in humans

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Regional Concentrations of Insulin in the Rat Brain*

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Localization and characterization of insulin receptors in rat brain and pituitary gland using in vitro autoradiography and computerized densitometry

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Vascular transport of insulin to rat cardiac muscle. Central role of the capillary endothelium

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Decreased effect of insulin to stimulate skeletal muscle blood flow in obese man. A novel mechanism for insulin resistance

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Pharmacodynamics of insulin following intravenous and enteral administrations of porcine-zinc insulin to rats

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Insulin receptors are widely distributed in the central nervous system of the rat

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Accessibility of low-molecular-mass molecules to the median eminence and arcuate hypothalamic nucleus of adult mouse

3 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Cross-talk between the insulin and leptin signaling systems in rat hypothalamus.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Decreasing hypothalamic insulin receptors causes hyperphagia and insulin resistance in rats

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Mode of transcapillary transport of insulin and insulin analog NN304 in dog hindlimb: evidence for passive diffusion

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5635907

Insulin differentially regulates systemic and skeletal muscle vascular resistance

14 August 2018

1 reference

12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

12 December 2020

Measuring bone blood supply in mice using fluorescent microspheres

1 reference

12 December 2020

Restricted passage of insulin across capillary endothelium in perfused rat adipose tissue

1 reference

12 December 2020

Interaction between insulin sensitivity and muscle perfusion on glucose uptake in human skeletal muscle: evidence for capillary recruitment

1 reference

12 December 2020

Receptor-mediated transport of insulin across endothelial cells

1 reference

12 December 2020

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1710625114

1 reference

1 July 2018

PMC publication ID

5635907

1 reference

1 July 2018

PubMed publication ID

28923931

1 reference

1 July 2018