Wikidata

(Q4812911)

English

ATR serine/threonine kinase

mammalian protein found in Homo sapiens

  • ataxia telangiectasia and Rad3-related protein
  • MEC1, mitosis entry checkpoint 1, homolog
  • ATR
  • FRAP-related protein-1
  • serine/threonine-protein kinase ATR
  • FRAP-related protein 1
In more languages

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
8 April 2019
stated in
Activation of the ATR kinase by the RPA-binding protein ETAA1
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
ETAA1 acts at stalled replication forks to maintain genome integrity
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
Cdc5L interacts with ATR and is required for the S-phase cell-cycle checkpoint
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
Reconstitution of a human ATR-mediated checkpoint response to damaged DNA.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
Functional genomic screens identify CINP as a genome maintenance protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
Cyclin-dependent kinase 9-cyclin K functions in the replication stress response
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
retrieved
8 April 2019
stated in
A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IPI
protein serine/threonine kinase activity
determination method
IEA
IDA
TAS
7 references
retrieved
24 April 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
TAS
retrieved
24 April 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
IEA
retrieved
24 April 2018
stated in
Activation of the ATR kinase by the RPA-binding protein ETAA1
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
24 April 2018
stated in
ETAA1 acts at stalled replication forks to maintain genome integrity
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
24 April 2018
stated in
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
24 April 2018
stated in
A role for ATR in the DNA damage-induced phosphorylation of p53
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13535&geneProductId=UniProtKB:Q13535
determination method
IDA
protein serine/threonine kinase activity
determination method
IBA
IDA
IEA
TAS
8 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IEA
retrieved
8 April 2019
stated in
Activation of the ATR kinase by the RPA-binding protein ETAA1
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
8 April 2019
stated in
ETAA1 acts at stalled replication forks to maintain genome integrity
GOA
curator
UniProt
UniProt protein ID
Q13535
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
8 April 2019
stated in
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
8 April 2019
stated in
A role for ATR in the DNA damage-induced phosphorylation of p53
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13535
determination method
IBA
cell component
biological process

Identifiers

Freebase ID
/m/02plbh7
0 references
 
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