(Q48157199)

9 February 2018

title

Caveolin-3 upregulation activates beta-secretase-mediated cleavage of the amyloid precursor protein in Alzheimer's disease. (English)

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9 February 2018

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Nishiyama K

1

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9 February 2018

Trapp BD

2

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9 February 2018

Ikezu T

3

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9 February 2018

Ransohoff RM

4

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9 February 2018

Tomita T

5

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9 February 2018

Iwatsubo T

6

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9 February 2018

Kanazawa I

7

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9 February 2018

Hsiao KK

8

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9 February 2018

Lisanti MP

9

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9 February 2018

Okamoto T

10

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9 February 2018

language of work or name

English

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publication date

1 August 1999

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9 February 2018

published in

Journal of Neuroscience

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9 February 2018

volume

19

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9 February 2018

page(s)

6538-6548

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9 February 2018

issue

15

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9 February 2018

Amyloid load and neural elements in Alzheimer's disease and nondemented individuals with high amyloid plaque density.

cites work

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Cell biology of the amyloid beta-protein precursor and the mechanism of Alzheimer's disease

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Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E.

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Interferon-beta specifically inhibits interferon-gamma-induced class II major histocompatibility complex gene transcription in a human astrocytoma cell line

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Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein

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The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

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Anti-inflammatory drugs in the fight against Alzheimer's disease

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Normal and abnormal biology of the beta-amyloid precursor protein

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Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol.

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12 December 2020

Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane

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Mutational analysis of the properties of caveolin-1. A novel role for the C-terminal domain in mediating homo-typic caveolin-caveolin interactions

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Ligand-dependent G protein coupling function of amyloid transmembrane precursor

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Animal models of ALS.

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Differential effects of the swedish mutant amyloid precursor protein on beta-amyloid accumulation and secretion in neurons and nonneuronal cells

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12 December 2020

Expression of caveolin-3 in skeletal, cardiac, and smooth muscle cells. Caveolin-3 is a component of the sarcolemma and co-fractionates with dystrophin and dystrophin-associated glycoproteins

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12 December 2020

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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12 December 2020

Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury

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12 December 2020

Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation

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12 December 2020

Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types.

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A detergent-insoluble membrane compartment contains A beta in vivo.

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12 December 2020

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

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12 December 2020

Determination of amyloid beta protein precursors harboring active form of proteinase inhibitor domains in cerebrospinal fluid of Alzheimer's disease patients by trypsin-antibody sandwich ELISA.

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12 December 2020

A detergent-free method for purifying caveolae membrane from tissue culture cells

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12 December 2020

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

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12 December 2020

Regulation of brain G-protein go by Alzheimer's disease gene presenilin-1.

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12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 December 2020

Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

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12 December 2020

Expression of amyloid precursor protein (APP) in rat brain and cultured neural cells.

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12 December 2020

Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

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12 December 2020

Beta-amyloid precursor protein cleavage by a membrane-bound protease

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12 December 2020

Protease inhibitors generate cytotoxic fragments from Alzheimer amyloid protein precursor in cDNA-transfected glioma cells

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12 December 2020

Subcellular distribution and turnover of presenilins in transfected cells

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12 December 2020

Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

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12 December 2020

Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.

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12 December 2020

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

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12 December 2020

Identification of caveolin and caveolin-related proteins in the brain.

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12 December 2020

Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins

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12 December 2020

Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).

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12 December 2020

Functional rafts in cell membranes

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12 December 2020

VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles

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12 December 2020

Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe

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12 December 2020

Soluble derivatives of the beta amyloid protein precursor in cerebrospinal fluid: alterations in normal aging and in Alzheimer's disease

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12 December 2020

Tyrosine kinase receptors concentrated in caveolae-like domains from neuronal plasma membrane

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12 December 2020

Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

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12 December 2020

Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle

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12 December 2020

Complementary DNA for the mouse homolog of the human amyloid beta protein precursor.

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12 December 2020

Identifiers

PubMed ID

10414982

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9 February 2018