(Q48264091)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

title

Arsenic trioxide degrades NPM-ALK fusion protein and inhibits growth of ALK-positive anaplastic large cell lymphoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Eric Tse

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

author name string

W Piao

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

L M Yue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Y-L Kwong

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

publication date

31 October 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

volume

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

page(s)

522-526

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/leu.2016.311

26 March 2020

exact match

0 references

cites work

ALK- anaplastic large-cell lymphoma is clinically and immunophenotypically different from both ALK+ ALCL and peripheral T-cell lymphoma, not otherwise specified: report from the International Peripheral T-Cell Lymphoma Project

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Survival of patients with peripheral T-cell lymphoma after first relapse or progression: spectrum of disease and rare long-term survivors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Pathobiology of NPM-ALK and variant fusion genes in anaplastic large cell lymphoma and other lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Pathobiology of ALK+ anaplastic large-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

What have we learnt from mouse models of NPM-ALK-induced lymphomagenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Arsenic trioxide and all-trans retinoic acid target NPM1 mutant oncoprotein levels and induce apoptosis in NPM1-mutated AML cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

PML/RARA oxidation and arsenic binding initiate the antileukemia response of As2O3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Arsenic trioxide: safety issues and their management

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Trolox enhances the anti-lymphoma effects of arsenic trioxide, while protecting against liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2016.311

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cells

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27795556

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27795556

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of phosphatidylinositol 3-kinase-Akt pathway in nucleophosmin/anaplastic lymphoma kinase-mediated lymphomagenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27795556

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LEU.2016.311

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27795556%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

1 reference